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ICAM1 Antikörper

ICAM1 Reaktivität: Ratte FACS, IP, IHC (fro), IHC (f), IHC (zinc) Wirt: Maus Monoclonal 1A29 unconjugated
Produktnummer ABIN2689331
  • Target Alle ICAM1 Antikörper anzeigen
    ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
    Reaktivität
    • 221
    • 87
    • 38
    • 7
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    Ratte
    Wirt
    • 120
    • 120
    • 32
    • 4
    • 2
    • 1
    • 1
    • 1
    Maus
    Klonalität
    • 159
    • 119
    • 1
    Monoklonal
    Konjugat
    • 126
    • 26
    • 25
    • 21
    • 12
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ICAM1 Antikörper ist unkonjugiert
    Applikation
    • 170
    • 159
    • 64
    • 63
    • 46
    • 40
    • 37
    • 35
    • 31
    • 28
    • 25
    • 21
    • 12
    • 10
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Zinc-fixed Sections) (IHC (zinc))
    Marke
    BD Pharmingen™
    Produktmerkmale
    The 1A29 antibody reacts with ICAM-1 (CD54), an 85 kDa surface glycoprotein expressed on vascular endothelium in lymphoid tissues, thymic stromal cells, peripheral blood monocytes, peritoneal macrophages and mast cells, dendritic cells, and weakly on peripheral lymphocytes and thymocytes. ICAM-1 is a ligand for LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). Its expression is upregulated on activated lymphocytes and endothelial cells. 1A29 mAb inhibits PMA-induced aggregation of PHA-stimulated splenic blasts, as well as the adhesion of mitogen-stimulated blasts to HEV-derived endothelial cells and purified ICAM-1. It has also been reported that 1A29 antibody can inhibit leukocyte infiltration in in vivo systems, blocks induction of experimental allergic encephalomyelitis, and reduces NK-cell adhesion to tumor cells. The effects of in vivo administration of the 1A29 monoclonal antibody have been thoroughly investigated. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature.

    BD Pharmingen™ Purified Mouse Anti-Rat CD54 - Purified - Clone 1A29 - Isotype Mouse IgG1, κ - Reactivity Rat - 0.5 mg
    Aufreinigung
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogen
    Rat HEV-Derived Cell Line Ax
    Klon
    1A29
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product ICAM1 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store undiluted at 4°C.
  • Machelska, Mousa, Brack, Schopohl, Rittner, Schafer, Stein: "Opioid control of inflammatory pain regulated by intercellular adhesion molecule-1." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 22, Issue 13, pp. 5588-96, (2002) (PubMed).

    Liu, Zhang, Jenkins, MacPherson: "Dendritic cell heterogeneity in vivo: two functionally different dendritic cell populations in rat intestinal lymph can be distinguished by CD4 expression." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 161, Issue 3, pp. 1146-55, (1998) (PubMed).

    Watanabe, Arakawa, Fukuda, Higuchi, Kobayashi: "Role of neutrophils in a rat model of gastric ulcer recurrence caused by interleukin-1 beta." in: The American journal of pathology, Vol. 150, Issue 3, pp. 971-9, (1997) (PubMed).

    Chen-Woan, Delaney, Fournier, Wakizaka, Murase, Fung, Starzl, Demetris: "In vitro characterization of rat bone marrow-derived dendritic cells and their precursors." in: Journal of leukocyte biology, Vol. 59, Issue 2, pp. 196-207, (1996) (PubMed).

    Willenborg, Staykova, Miyasaka: "Short term treatment with soluble neuroantigen and anti-CD11a (LFA-1) protects rats against autoimmune encephalomyelitis: treatment abrogates autoimmune disease but not autoimmunity." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 157, Issue 5, pp. 1973-80, (1996) (PubMed).

    Fox, Jewell, Whitacre: "Rat peritoneal mast cells present antigen to a PPD-specific T cell line." in: Cellular immunology, Vol. 158, Issue 1, pp. 253-64, (1994) (PubMed).

    Springer: "Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm." in: Cell, Vol. 76, Issue 2, pp. 301-14, (1994) (PubMed).

    Westermann, Nagahori, Walter, Heerwagen, Miyasaka, Pabst et al.: "B and T lymphocyte subsets enter peripheral lymph nodes and Peyer's patches without preference in vivo: no correlation occurs between their localization in different types of high endothelial venules ..." in: European journal of immunology, Vol. 24, Issue 10, pp. 2312-6, (1994) (PubMed).

    Bañuls, Alvarez, Ferrero, Zapata, Ardavin: "Cell-surface marker analysis of rat thymic dendritic cells." in: Immunology, Vol. 79, Issue 2, pp. 298-304, (1993) (PubMed).

    Turunen, Ustinov, Renkonen: "Adhesion molecules involved in protein kinase A- and C-dependent lymphocyte adherence to microvascular endothelial cells." in: Scandinavian journal of immunology, Vol. 37, Issue 3, pp. 282-8, (1993) (PubMed).

    Yamazaki, Seko, Tamatani, Miyasaka, Yagita, Okumura, Nagai, Yazaki: "Expression of intercellular adhesion molecule-1 in rat heart with ischemia/reperfusion and limitation of infarct size by treatment with antibodies against cell adhesion molecules." in: The American journal of pathology, Vol. 143, Issue 2, pp. 410-8, (1993) (PubMed).

    Tamatani, Kotani, Miyasaka: "Characterization of the rat leukocyte integrin, CD11/CD18, by the use of LFA-1 subunit-specific monoclonal antibodies." in: European journal of immunology, Vol. 21, Issue 3, pp. 627-33, (1991) (PubMed).

    Xia, Schneeberger, McCarthy, Kradin: "Accessory cells of the lung. II. Ia+ pulmonary dendritic cells display cell surface antigen heterogeneity." in: American journal of respiratory cell and molecular biology, Vol. 5, Issue 3, pp. 276-83, (1991) (PubMed).

  • Target
    ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
    Andere Bezeichnung
    CD54 (ICAM1 Produkte)
    Synonyme
    BB2 antikoerper, CD54 antikoerper, P3.58 antikoerper, Icam-1 antikoerper, Ly-47 antikoerper, MALA-2 antikoerper, ICAM antikoerper, ICAM-1 antikoerper, ICAM1 antikoerper, intercellular adhesion molecule 1 antikoerper, intercellular adhesion molecule-1 antikoerper, ICAM1 antikoerper, Icam1 antikoerper, ICAM-1 antikoerper
    Substanzklasse
    Viral Protein
    Hintergrund
    Synonyms: ICAM-1
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
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