CD42a Antikörper

Produktnummer ABIN2689252

Produktdetails anti-CD42a Antikörper

Target: CD42a (GP9) (Glycoprotein IX (Platelet) (GP9))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD42a Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Marke: BD Pharmingen™

Produktmerkmale: Reacts with a 17-22kD, single chain integral membrane glycoprotein, also known as GPIX. CD42a forms a noncovalently linked complex (GPIb/GPIX/GPV) with CD42b, CD42c and CD42d. It is expressed on platelets and megakaryocytes and is absent on the platelets of patients with Bernadr-Soulier Syndrome (BSS). Although the CD42a function is not fully understood, GPIX glycoprotein is important for the assembly and membrane expression of the complex and for the maintenance of the functional conformation of CD42b (GPIb). Profile of resting platelets analyzed by flow cytometry

BD Pharmingen™ Purified Mouse Anti-Human CD42a - Purified - Clone ALMA.16 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg

Aufreinigung: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Klon: ALMA-16

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 4°C.

Referenzen für anti-CD42a Antikörper (ABIN2689252)

Schick, Walker: "The acylation of megakaryocyte proteins: glycoprotein IX is primarily myristoylated while glycoprotein Ib is palmitoylated." in: Blood, Vol. 87, Issue 4, pp. 1377-84, (1996) (PubMed).

Hickey, Williams, Roth: "Human platelet glycoprotein IX: an adhesive prototype of leucine-rich glycoproteins with flank-center-flank structures." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, Issue 17, pp. 6773-7, (1989) (PubMed).

Fox, Aggerbeck, Berndt: "Structure of the glycoprotein Ib.IX complex from platelet membranes." in: The Journal of biological chemistry, Vol. 263, Issue 10, pp. 4882-90, (1988) (PubMed).

Details zu CD42a

Target: CD42a (GP9) (Glycoprotein IX (Platelet) (GP9))

Andere Bezeichnung: CD42a (GP9 Produkte)

Synonyme: cd42a antikoerper, gpix antikoerper, GP9 antikoerper, GPIX antikoerper, Cd42 antikoerper, CD42a antikoerper, glycoprotein IX platelet antikoerper, glycoprotein IX platelet L homeolog antikoerper, glycoprotein IX (platelet) antikoerper, glycoprotein 9 (platelet) antikoerper, GP9 antikoerper, gp9.L antikoerper, Gp9 antikoerper