CD151 Antikörper

Produktnummer ABIN2688986

Produktdetails anti-CD151 Antikörper

Target: CD151

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD151 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Marke: BD Pharmingen™

Produktmerkmale: Reacts with platelet-endothelial cell tetraspan antigen-3 (PETA-3), a 27 kD membrane glycoprotein, expressed on platelets, megakaryocytes, lymphocytes (weak), monocytes, endothelial cells and epithelial cells. PETA-3 (CD151) associates with β1 integrin in certain tissues. This has also been shown with other tetraspan superfamily members, like CD9, CD63 and α5β1. Reports indicate that this association or colocalization of CD151 with β1 integrin in tissues suggests a functional role of this molecule, however, this role has not been elucidated yet. It has also been reported that antibody 14A2.H1 is capable of platelet activation in vitro. Studies showed that different clones of CD151 monoclonal antibodies display strikingly different patterns of binding to human haemopoietic cells and tissue sections, and that this is due at least in part to the presence of the protein in complexes with different integrins. Profile of peripheral blood platelets analyzed by flow cytometry

BD Pharmingen™ Purified Mouse Anti-Human CD151 - Purified - Clone 14A2.H1 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg

Aufreinigung: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Klon: 14A2-H1

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 4°C.

Referenzen für anti-CD151 Antikörper (ABIN2688986)

Geary, Cambareri, Sincock, Fitter, Ashman: "Differential tissue expression of epitopes of the tetraspanin CD151 recognised by monoclonal antibodies." in: Tissue antigens, Vol. 58, Issue 3, pp. 141-53, (2001) (PubMed).

Sincock, Mayrhofer, Ashman: "Localization of the transmembrane 4 superfamily (TM4SF) member PETA-3 (CD151) in normal human tissues: comparison with CD9, CD63, and alpha5beta1 integrin." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 45, Issue 4, pp. 515-25, (1997) (PubMed).

Fitter, Tetaz, Berndt, Ashman: "Molecular cloning of cDNA encoding a novel platelet-endothelial cell tetra-span antigen, PETA-3." in: Blood, Vol. 86, Issue 4, pp. 1348-55, (1995) (PubMed).

Details zu CD151

Target: CD151

Andere Bezeichnung: CD151 (CD151 Produkte)

Synonyme: CD151 antikoerper, MGC83668 antikoerper, gp27 antikoerper, mer2 antikoerper, raph antikoerper, sfa1 antikoerper, peta-3 antikoerper, tspan24 antikoerper, PETA-3 antikoerper, SFA-1 antikoerper, Tspan24 antikoerper, GP27 antikoerper, MER2 antikoerper, RAPH antikoerper, SFA1 antikoerper, TSPAN24 antikoerper, CD151 molecule antikoerper, CD151 molecule (Raph blood group) L homeolog antikoerper, CD151 molecule (Raph blood group) antikoerper, CD151 antigen antikoerper, CD151 antikoerper, cd151.L antikoerper, cd151 antikoerper, Cd151 antikoerper

Hintergrund: Synonyms: PETA-3