Thrombomodulin Antikörper

Produktnummer ABIN2688974

Produktdetails anti-Thrombomodulin Antikörper

Target: Thrombomodulin (THBD)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Thrombomodulin Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Fluorescence Microscopy (FM)

Marke: BD Pharmingen™

Produktmerkmale: Reacts with a 75 kDa, a single chain, type I membrane glycoprotein referred to as thrombomodulin and fetomodulin. CD141 is expressed on endothelial cells, smooth muscle cells, epithelial cells, synovial lining cells, and keratinocytes. It is also found on megakaryocytes, peripheral blood moncytes, and neutrophils, but not on lymphocytes. Reports indicate that CD 141 plays an important role in Protein C activation and the initiation of the Protein C anticoagulant pathway. Thrombin loses its procagulant function when it binds to CD141, and the CD141/thrombin complex is able to activate Protein C. This product is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of peripheral blood monocytes analyzed by flow cytometry.

BD Pharmingen™ Purified Mouse Anti-Human CD141 - Purified - Clone 1A4 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg

Aufreinigung: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Klon: 1A4

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 4°C.

Referenzen für anti-Thrombomodulin Antikörper (ABIN2688974)

Teasdale, Bird, Bird: "Internalization of the anticoagulant thrombomodulin is constitutive and does not require a signal in the cytoplasmic domain." in: Immunology and cell biology, Vol. 72, Issue 6, pp. 480-8, (1995) (PubMed).

Details zu Thrombomodulin

Target: Thrombomodulin (THBD)

Andere Bezeichnung: CD141 (THBD Produkte)

Synonyme: AHUS6 antikoerper, BDCA3 antikoerper, CD141 antikoerper, THPH12 antikoerper, THRM antikoerper, TM antikoerper, AI385582 antikoerper, THBD antikoerper, HAST antikoerper, HAST3 antikoerper, M-PST antikoerper, ST1A3/ST1A4 antikoerper, ST1A5 antikoerper, STM antikoerper, TL-PST antikoerper, thrombomodulin antikoerper, sulfotransferase family 1A member 3 antikoerper, THBD antikoerper, Thbd antikoerper, SULT1A3 antikoerper

Hintergrund: Synonyms: Thrombomodulin