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FLT3 Antikörper

FLT3 Reaktivität: Human FACS Wirt: Maus Monoclonal 4G8 unconjugated
Produktnummer ABIN2688960
  • Target Alle FLT3 Antikörper anzeigen
    FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
    Reaktivität
    • 171
    • 57
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 170
    • 17
    • 6
    • 1
    Maus
    Klonalität
    • 171
    • 23
    Monoklonal
    Konjugat
    • 70
    • 17
    • 13
    • 11
    • 10
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 1
    Dieser FLT3 Antikörper ist unkonjugiert
    Applikation
    • 132
    • 79
    • 54
    • 54
    • 41
    • 26
    • 20
    • 14
    • 9
    • 9
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Marke
    BD Pharmingen™
    Produktmerkmale
    Reacts with FMS-like tyrosine kinase 3 (flt3), a 155-160 kD, class III tyrosine kinase receptor (CD135), which is structurally related to the receptors for PDGF, SCF-1 and kit ligand. CD135 is expressed on multipotential, myelomonocytic and primitive B-cell progenitors. The most primitive hematopoietic progenitor cells express low levels of CD135. CD135 plays the role of growth factor receptor for early hematopoietic progenitors. Reports from studies with knockout mice have shown that targeted CD135 disruption impaired the development of primitive progenitor cells of all hematopoietic lineages with significant impact on lymphopoietic precursors. Profile of REH cell line analyzed by flow cytometry

    BD Pharmingen™ Purified Mouse Anti-Human CD135 - Purified - Clone 4G8 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg
    Aufreinigung
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Klon
    4G8
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product FLT3 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store undiluted at 4°C.
  • Rappold, Ziegler, Köhler, Marchetto, Rosnet, Birnbaum, Simmons, Zannettino, Hill, Neu, Knapp, Alitalo, Alitalo, Ullrich, Kanz, Bühring: "Functional and phenotypic characterization of cord blood and bone marrow subsets expressing FLT3 (CD135) receptor tyrosine kinase." in: Blood, Vol. 90, Issue 1, pp. 111-25, (1997) (PubMed).

    Rusten, Lyman, Veiby, Jacobsen: "The FLT3 ligand is a direct and potent stimulator of the growth of primitive and committed human CD34+ bone marrow progenitor cells in vitro." in: Blood, Vol. 87, Issue 4, pp. 1317-25, (1996) (PubMed).

    Mackarehtschian, Hardin, Moore, Boast, Goff, Lemischka: "Targeted disruption of the flk2/flt3 gene leads to deficiencies in primitive hematopoietic progenitors." in: Immunity, Vol. 3, Issue 1, pp. 147-61, (1995) (PubMed).

    Rosnet, Schiff, Pébusque, Marchetto, Tonnelle, Toiron, Birg, Birnbaum: "Human FLT3/FLK2 gene: cDNA cloning and expression in hematopoietic cells." in: Blood, Vol. 82, Issue 4, pp. 1110-9, (1993) (PubMed).

  • Target
    FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
    Andere Bezeichnung
    CD135 (FLT3 Produkte)
    Synonyme
    FLT3 antikoerper, B230315G04 antikoerper, CD135 antikoerper, Flk-2 antikoerper, Flk2 antikoerper, Flt-3 antikoerper, Ly72 antikoerper, wmfl antikoerper, FLK-2 antikoerper, FLK2 antikoerper, STK1 antikoerper, fms related tyrosine kinase 3 antikoerper, FMS-like tyrosine kinase 3 antikoerper, fms-related tyrosine kinase 3 antikoerper, FLT3 antikoerper, Flt3 antikoerper
    Pathways
    RTK Signalweg
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