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Integrin beta 4 Antikörper

ITGB4 Reaktivität: Human WB, IP, FM, ICS Wirt: Maus Monoclonal 450 unconjugated
Produktnummer ABIN2688877
  • Target Alle Integrin beta 4 (ITGB4) Antikörper anzeigen
    Integrin beta 4 (ITGB4)
    Reaktivität
    • 84
    • 30
    • 26
    • 3
    • 3
    • 1
    Human
    Wirt
    • 57
    • 38
    • 12
    • 2
    Maus
    Klonalität
    • 58
    • 51
    Monoklonal
    Konjugat
    • 58
    • 9
    • 8
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Integrin beta 4 Antikörper ist unkonjugiert
    Applikation
    • 55
    • 47
    • 32
    • 30
    • 21
    • 16
    • 15
    • 13
    • 13
    • 9
    • 8
    • 8
    • 7
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Fluorescence Microscopy (FM), Intracellular Staining (ICS)
    Marke
    BD Pharmingen™
    Produktmerkmale
    Reacts with CD104, integrin β4 chain, a 205 kDa transmembrane glycoprotein, associated with CD49f (integrin α6 chain) to form the α6/β4 (CD49f/CD104) complex. CD104 is expressed on epithelial cells, Schwann cells, and some tumor cells. The CD49f/CD104 complex is located in the hemidesmosomes of the epidermis, suggesting its role in epidermal cell-basement membrane adhesion. The clone 450-11A recognizes the cytoplasmic domain of human CD104. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of intracellular A431 cells, an epidermal carcinoma cell line, analyzed by flow cytometry

    BD Pharmingen™ Purified Mouse Anti-Human CD104 - Purified - Clone 450-11A - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg
    Aufreinigung
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Klon
    450
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product ITGB4 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store undiluted at 4°C.
  • Jones, Kurpakus, Cooper, Quaranta: "A function for the integrin alpha 6 beta 4 in the hemidesmosome." in: Cell regulation, Vol. 2, Issue 6, pp. 427-38, (1991) (PubMed).

    Sonnenberg, Calafat, Janssen, Daams, van der Raaij-Helmer, Falcioni, Kennel, Aplin, Baker, Loizidou: "Integrin alpha 6/beta 4 complex is located in hemidesmosomes, suggesting a major role in epidermal cell-basement membrane adhesion." in: The Journal of cell biology, Vol. 113, Issue 4, pp. 907-17, (1991) (PubMed).

    Kennel, Epler, Lankford, Foote, Dickas, Canamucio, Cavalierie, Cosimelli, Venturo, Falcioni: "Second generation monoclonal antibodies to the human integrin alpha 6 beta 4." in: Hybridoma, Vol. 9, Issue 3, pp. 243-55, (1990) (PubMed).

    Tamura, Rozzo, Starr, Chambers, Reichardt, Cooper, Quaranta: "Epithelial integrin alpha 6 beta 4: complete primary structure of alpha 6 and variant forms of beta 4." in: The Journal of cell biology, Vol. 111, Issue 4, pp. 1593-604, (1990) (PubMed).

    Hemler, Crouse, Sonnenberg: "Association of the VLA alpha 6 subunit with a novel protein. A possible alternative to the common VLA beta 1 subunit on certain cell lines." in: The Journal of biological chemistry, Vol. 264, Issue 11, pp. 6529-35, (1989) (PubMed).

  • Target
    Integrin beta 4 (ITGB4)
    Andere Bezeichnung
    CD104 (ITGB4 Produkte)
    Synonyme
    AA407042 antikoerper, C230078O20 antikoerper, CD104 antikoerper, integrin subunit beta 4 antikoerper, integrin beta 4 antikoerper, ITGB4 antikoerper, Itgb4 antikoerper
    Hintergrund
    Synonyms: Integrin β4 chain
    Pathways
    Integrin Complex
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