ICAM2 Antikörper

Produktnummer ABIN2688871

Produktdetails anti-ICAM2 Antikörper

Target: ICAM2 (Intercellular Adhesion Molecule 2 (ICAM2))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser ICAM2 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Blocking Reagent (BR)

Marke: BD Pharmingen™

Produktmerkmale: The 3C4 (mIC2/4) antibody reacts with the mouse ICAM-2 (CD102) cell surface glycoprotein, a ligand for LFA-1. CD102 is constitutively expressed on endothelial cells, T and B lymphocytes, and alveolar walls. It is also expressed on a variety of leukocyte cell lines. CD102 does not appear to be involved in the development of hematopoietic cells. In a model for allergic asthma, endothelial CD102 mediates the transmigration of eosinophils (but not lymphocytes, monocytes, or macrophages) into the airway lumen. The 3C4 (mIC2/4) antibody blocks interactions between ICAM-2 and LFA-1. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature.

BD Pharmingen™ Purified Rat Anti-Mouse CD102 - Purified - Clone 3C4(mIC2/4) - Isotype Rat IgG2a, κ - Reactivity Ms - 0.5 mg

Aufreinigung: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogen: Transfected Cell Line

Klon: 3C4

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 4°C.

Referenzen für anti-ICAM2 Antikörper (ABIN2688871)

Gerwin, Gonzalo, Lloyd, Coyle, Reiss, Banu, Wang, Xu, Avraham, Engelhardt, Springer, Gutierrez-Ramos: "Prolonged eosinophil accumulation in allergic lung interstitium of ICAM-2 deficient mice results in extended hyperresponsiveness." in: Immunity, Vol. 10, Issue 1, pp. 9-19, (1999) (PubMed).

Xu, Bickford, Luther, Carpenito, Takei, Springer: "Characterization of murine intercellular adhesion molecule-2." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 156, Issue 12, pp. 4909-14, (1996) (PubMed).

Xu, Tong, De Fougerolles, Springer: "Isolation, characterization, and expression of mouse ICAM-2 complementary and genomic DNA." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 149, Issue 8, pp. 2650-5, (1992) (PubMed).

Details zu ICAM2

Target: ICAM2 (Intercellular Adhesion Molecule 2 (ICAM2))

Andere Bezeichnung: CD102 (ICAM2 Produkte)

Synonyme: ICAM2 antikoerper, CD102 antikoerper, Icam-2 antikoerper, Ly-60 antikoerper, intercellular adhesion molecule 2 antikoerper, LOC506088 antikoerper, ICAM2 antikoerper, LOC616254 antikoerper, LOC100140873 antikoerper, Icam2 antikoerper

Hintergrund: Synonyms: ICAM-2