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beta-Catenin (CTNNB1) Antikörper

Antigen

beta-Catenin (CTNNB1)

Synonyme
CTNNB, FLJ25606, FLJ37923, DKFZp686D02253, Mesc, Catnb, ctnnb, id:ibd2058, wu:fb73e10, wu:fi81c06, wu:fk25h01, ARM, Beta-cat, Beta-catenin, EG:86E4.6, beta-cat-arm, l(1)2Bv, l(1)G0192, l(1)G0234, l(1) ... mehr anzeigen
Klonalität Monoklonal (15B8)
Wirt
Reaktivität
Alternativen

Rind (Kuh), Hund, Huhn, Human

Applikation
Alternativen Elektromobilitäts-Experimente (EMSA), Immunfluoreszenz (IF), Western Blot (WB)
Produktnummer ABIN267541
Menge 0.1 ml
Preis 370,00 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 7 bis 10 Werktagen

Produktbeschreibung

Weitere Bezeichnung Catenin beta-1
Gen-ID 1499
Immunogen Recombinant full length protein (Chicken).
Format Ascites
Isotyp IgG1  (Passende Sekundärantikörper)
Klon 15B8
Beschreibung The distinct peripheral cytosolic proteins, alpha, beta and gamma catenin (102, 94 and86 kDa) are found in many tissues bind to the conserved cytoplasmic tail domain of thecell adhesion cadherins. Catenins link E cadherin to other integral membrane orcytoplasmic proteins and are modulated by Wnt1 proto oncogene. The central coreregion of beta catenin is involved in mediation of cadherin catenin complex interactionwith EGFR. Beta-Catenin-mediated signalling is involved at several stages of vertebrateneural development. Alternate Names: anti-Beta catenin antibody, anti-Cadherin associated protein antibody, anti-Catenin beta1 antibody, anti-CATNB antibody, anti-CTNNB antibody, anti-CTNNB1 antibody.
Spezifität Recognizes beta-catenin in immunoblotting (94kD). Does not recognize plakoglobin. Species Reactivity: Cross-reacts with Cow, Dog and Human.Not yet tested in other species. Localization: Cytoplasmic when it is unstabilized (high level of phosphorylation) or bound to CDH1.Translocates to the nucleus when it is stabilized (low level of phosphorylation).
Synonyme CTNNB, FLJ25606, FLJ37923, DKFZp686D02253, Mesc, Catnb, ctnnb, id:ibd2058, wu:fb73e10, wu:fi81c06, wu:fk25h01, ARM, Beta-cat, Beta-catenin, EG:86E4.6, beta-cat-arm, l(1)2Bv, l(1)G0192, l(1)G0234, l(1)G0410, l(1)arm, t12687 ALR Dm, DmelCG11579, CG11579, beta-catenin, ctnnb1, MGC79992, MGC132060, Cibeta-catenin, CTNNB1, MGC52601, LOC576711, Ctnnb1, MGC139922

Anwendungen

Applikationshinweise Suggested working dilutions: immunofluorescence 1:1000,Gel Super Shift Assays,Positive Controls: Cultured MDBK cells or cell extract.
Buffer Ascitic fluid with 0.1% sodium azide. Preservative: 0.1% sodium azide.
Lagerung Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles.
Forschungsgebiet Signaltransduktion
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen

Alternativen zu Antigen "beta-Catenin (CTNNB1)", Typ "Antikörper" finden
Wirte Kaninchen (187), Maus (61)
Reaktivitäten Human (230), Maus (155), Ratte (Rattus) (138), Huhn (28), Hund (12), Rind (Kuh) (7), Schwein (6), Xenopus laevis (5), Hamster (2), Affe (1), Kaninchen (1), Schaf (1)
Applikationen Western Blot (WB) (219), Immunfluoreszenz (IF) (71), Immunpräzipitation (IP) (63), Enzyme Immunoassay (EIA) (52), Immunhistochemie (Paraffinschnitte) (IHC (p)) (50), Immunhistochemie (IHC) (40), ELISA (30), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (20), Durchflusszytometrie (FACS) (19), Dot Blot (Dot) (8), Immunzytochemie (ICC) (5), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunoelectron Microscopy (IEM) (1)
Konjugate Biotin (5), Cy3 (2), FITC (2), HRP (2), Alexa Flour 488 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1), RBITC (1)
Epitope pSer33 (10), pSer37 (10), Ab-33 (5), Ab-37 (5), Ab-41/45 (5), C-Term (5), pSer33/37 (5), pThr41/Ser45 (5), pThr41/pSer45 (5), Ab-654 (3), pTyr654 (3), pTyr86 (3), exon 3 (2), pSer45 (2), Ab-489 (1), Core (1), dep27-37 (1), dep35-50 (1), pTyr489 (1)