Thyroglobulin (TG) Antikörper
| Antigen |
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| Synonyme |
TGN, TDH3, AITD3, Tgn, cog, MGC117699, TG, cb717 |
| Klonalität |
Monoklonal (TGB04) |
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Wirt
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Applikation
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 Alternativen Immunhistochemie (Gefrierschnitte) (IHC (fro)), Immunhistochemie (Paraffinschnitte) (IHC (p))
Immunhistochemie (Paraffinschnitte) (IHC (p)) (62), Enzyme Immunoassay (EIA) (46), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (31), ELISA (25), Western Blot (WB) (19), Immunhistochemie (IHC) (16), Radioimmunoassay (RIA) (14), Immunpräzipitation (IP) (11), Immunfluoreszenz (IF) (7), Durchflusszytometrie (FACS) (4), ELISA (Fangantikörper) (2), ELISA (Detektionsantikörper) (2), Dot Blot (Dot) (1), Immunoassay (IA) (1), Immunzytochemie (ICC) (1)
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| Produktnummer |
ABIN267513 |
| Menge |
0.5 ml (1 mg/ml) |
| Preis |
250,00 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
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Gen-ID
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7038, 21819, 24826
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Immunogen
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BALB/C mice were injected with purified human thyroglobulin.
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Isotyp
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IgG1 (Passende Sekundärantikörper)
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Klon
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TGB04
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Beschreibung
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Thyroglobulin is synthesized by the follicular epithelial cells of the thyroid. Thyroglobulinis the glycoprotein precursor to the thyroid hormones. Its synthesis and metabolismhave seemingly wasteful features. It has a molecular weight of 660,000, with 2 identicalsubunits of MW 300,000 and 10% sugars, yet its complete hydrolysis yields only 2 to 4molecules of the iodothyroxines T4 and T3. Baas et al. (1986) showed that the TG geneencodes an 8.7-kb mRNA, covers at least 300 kb of genomic DNA and contains at least37 exons separated by introns as large as 64 kb. A striking structural difference betweenthe 5-prime and 3-prime parts of the gene suggested that it is composed of 2evolutionarily different regions. The first 30 kb of DNA encodes 3 kb of the mRNAyielding an exon:intron ratio of 1:10, whereas the remaining 270 kb encodes 5.7 kb ofthe mRNA with a ratio of 1.47. Alternate Names: anti-AITD3 antibody, anti-hTG antibody, anti-Tgn antibody.
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Spezifität
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This antibody is specific to 330 kD protein. Species Reactivity: Cross-reacts with Dog, Human, Mouse and Rat. Not yet tested in other species. Localization: Secreted.
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Applikationshinweise
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Positive Controls: Thyroid.
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Konzentration
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1 mg/ml
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Buffer
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Constituents: PBS. Preservative: 0.05% sodium azide.
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Lagerung
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Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles.
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Forschungsgebiet
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Hormone
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "Thyroglobulin (TG)", Typ "Antikörper" finden
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Wirte
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Maus (105), Kaninchen (40), Schaf (1)
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Reaktivitäten
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Human (130), Rind (Kuh) (9), Maus (8), Ratte (Rattus) (7), Schwein (4), Hund (3), Ziege (3), Meerschweinchen (3), Kaninchen (3), Katze (2), Schaf (1)
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Applikationen
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Immunhistochemie (Paraffinschnitte) (IHC (p)) (62), Enzyme Immunoassay (EIA) (46), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (31), ELISA (25), Western Blot (WB) (19), Immunhistochemie (IHC) (16), Radioimmunoassay (RIA) (14), Immunpräzipitation (IP) (11), Immunfluoreszenz (IF) (7), Durchflusszytometrie (FACS) (4), ELISA (Fangantikörper) (2), ELISA (Detektionsantikörper) (2), Dot Blot (Dot) (1), Immunoassay (IA) (1), Immunzytochemie (ICC) (1)
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Konjugate
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FITC (4), Biotin (2)
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Epitope
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T3-specific (3), T4-specific (2)
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