Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1) Antikörper

Antigen: Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1)

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Maus, Ratte (Rattus)

Applikation: Immunpräzipitation (IP), Western Blot (WB)

Produktnummer: ABIN267181

Produktbeschreibung

Weitere Bezeichnung: G protein alpha inhibitor 1

Gen-ID: 2770, 14677, 25686

Immunogen: Synthetic peptide: K(346)NNLKDCGLF(355).Immunizing peptide corresponds to aminoacid residues 346-355 from human G protein alpha inhibitor 1/2.This sequence iscompletely conserved in human, rat, guinea pig, hamster, bovine, hydra, octopus,Xenopus, chicken, canine, spi ny dogfish, great pond snail, starfish, and Americanlobster.

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: The G protein family of signal transducers includes the alpha, beta, gamma subunitsand the effector which are most clearly distinguished by their different alpha chains. Thefamily also includes Gs and Gi, the stimulatory and inhibitory GTP-binding regulators ofadenylate cyclase, Go, a protein of unknown function that is abundantly expressed inbrain, and transducin 1 and 2, proteins involved in retinal phototransduction. The Gproteins possess GTPase activity and are components of a complex membranesignaling system that includes membrane-bound receptors. The system exists tomodulate extracellular signals as they are transmitted into the cell. Alternate Names: anti-Adenylate cyclase inhibiting G alpha antibody, anti-Adenylate cyclase inhibiting Galpha protein antibody, anti-Gi antibody, anti-Gi1 protein alpha subunit antibody,anti-Gi2 protein alpha subunit antibody, anti-GIP antibody, anti-GNAI 1 antibody,anti-GNAI 2 antibody, anti-GNAI 2B antibody, anti-GNAI1 antibody, anti-GNAI2antibody, anti-GNAI2 protein antibody, anti-GNAI2B antibody, anti-GTP bindingregulatory protein Gi alpha 2 chain antibody, anti-Guanine nucleotide binding protein (Gprotein) alpha inhibiting activity polypeptide 1 antibody, anti-Guanine nucleotide bindingprotein (G protein) alpha inhibiting activity polypeptide 2 antibody, anti-Guaninenucleotide binding protein alpha inhibiting activity polypeptide 1 antibody, anti-Guaninenucleotide binding protein alpha inhibiting activity polypeptide 2 antibody, anti-Guaninenucleotide binding protein G(i) alpha 1 subunit antibody, anti-Guanine nucleotide bindingprotein G(i) alpha 2 subunit antibody, anti-H LUCA15.1 antibody, anti-H LUCA16.1antibody.

Spezifität: ABIN267181 detects G protein alpha inhibitor 1/2 from human, rat, and mouse tissuesand cells. Species Reactivity: Cross-reacts with Human, Mouse and Rat.Expected to cross-react with Cow, Chicken,Dog, Guinea pig, Hamster, Starfish and Xenopus laevis due to sequence homology.Notyet tested in other species. Localization: Plasma membrane.

Anwendungen

Applikationshinweise: Western Blot: use at a concentration of 1 ug/ml.Optimaldilutions / concentrations should be determined by the end user.By Western blot, thisantibody detects an ~38 kDa protein representing G protein alpha inhibitor 1 + 2 fromHeLa cell lysate.

Buffer: PBS. Preservative: 1 mg/ml BSA, 0.05% sodium azide.

Lagerung: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Beschränkungen: Nur für Forschungszwecke einsetzbar