Calmodulin (CALM) Antikörper

Antigen: Calmodulin (CALM)

Synonyme: 3909, CAM, Cal, Cal49A, D-CaM, DmCalm, anon-EST:Posey59, dCaM, l(2)03909, l(2)3909, DmelCG8472, CG8472, calm2, cam, calm1, calmodulin, Cam, ACYPI000056, CALM3, CaM, CALM, Calmodulin, DKFZp469E1312, LOC100194628, PHKD, CAMII, PHKD2, FLJ99410, PHKD3, Calm, AI256814, AI327027, AI461935, AL024000, CaMI, CaMII

Klonalität: Monoklonal (2D1)

Wirt: Maus

Reaktivität: Rind (Kuh), Huhn, Dictyostelium, Ratte (Rattus)

Applikation: Immunhistochemie (Gefrierschnitte) (IHC (fro)), Enzyme Immunoassay (EIA), Immunfluoreszenz (IF), Western Blot (WB)

Produktnummer: ABIN266953

Produktbeschreibung

Weitere Bezeichnung: Calmodulin

Immunogen: Calmodulin purified from Dictyostelium discoideum.

Format: Ascites

Isotyp: IgG1  (Passende Sekundärantikörper)

Klon: 2D1

Beschreibung: Calmodulin is a small, highly conserved calcium binding protein found in all eukaryoticcells. With the capacity to bind up to four calcium ions, this 17 kDa protein acts as animportant intracellular receptor for regulatory calcium signals. As it binds calcium,calmodulin undergoes conformational changes which can increase its affinity for targetproteins. It acts both directly, through interaction with key target enzymes, and indirectly,via specific kinases. Studies have found that calmodulin participates in the regulationof several biological processes including energy and biosynthetic metabolism, cellmotility, exocytosis, cytoskeletal assembly, and intracellular modulation of both cAMPand calcium concentrations.

Spezifität: This antibody detects calmodulin. It does not detect parvalbumin, tropinin, S-100, ormyosin light chain kinase (MLCK). Species Reactivity: Cross-reacts with Cow, Chicken, E. coli, Rat, Chlamydomonas reinhardtii andDictyostelium discoideum. Not yet tested in other species.

Synonyme: 3909, CAM, Cal, Cal49A, D-CaM, DmCalm, anon-EST:Posey59, dCaM, l(2)03909, l(2)3909, DmelCG8472, CG8472, calm2, cam, calm1, calmodulin, Cam, ACYPI000056, CALM3, CaM, CALM, Calmodulin, DKFZp469E1312, LOC100194628, PHKD, CAMII, PHKD2, FLJ99410, PHKD3, Calm, AI256814, AI327027, AI461935, AL024000, CaMI, CaMII

Anwendungen

Applikationshinweise: Western Blot 1/500,Immunocytochemistry 1/100

Buffer: PBS with 0.05% sodium azide

Lagerung: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Forschungsgebiet: Krebs, Signaltransduktion, Hormone, Zytokine

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

anti-Calmodulin (CALM) antibody