Asparaginase Like 1 (ASRGL1) Antikörper (Biotin)

Antigen: Asparaginase Like 1 (ASRGL1)

Synonyme: ALP, ALP1, AU040643, AW060375, 2410004D18Rik, CRASH, FLJ22316, Gliap, Hiob2, ASRGL1, MGC133821

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Escherichia Coli (E. Coli)

Konjugat: Biotin

Applikation: Immunhistochemie (Gefrierschnitte) (IHC (fro)), Enzyme Immunoassay (EIA), Western Blot (WB)

Produktnummer: ABIN266841

Produktbeschreibung

Weitere Bezeichnung: L-asparaginase

Immunogen: Asparaginase (E. coli).

Isotyp: IgG

Beschreibung: Asparaginase is an enzyme purified from E. coli and Erwinia carotovora. It acts bydeaminating extracellular L asparagine, an amino acid that appears to be essential forprotein synthesis by some tumour cells which are unable to synthesise asparagine.Asparaginase from Erwinia carotovora is serologically and biochemically distinct fromasparaginase from E. coli, although its antineoplastic activity and toxicity is similar.Asparaginase is usually considered to be cell cycle phase nonspecific, but it may blocksome cells in G1 or S phase. Asparaginase reduces cellular and humoral immunity.E.coli contains two L asparaginase isoenzymes: L asparaginase I, a low affinity enzymelocated in the cytoplasm, and L asparaginase II, a high affinity secreted enzyme. Alternate Names: anti-L ASNase II antibody, anti-AnsA antibody, anti-AnsB antibody, anti-Colaspaseantibody, anti-Cytoplasmic asparaginase I antibody, anti-L ASNase I antibody, anti-LASNase II antibody, anti-L asparaginase 1 antibody, anti-L asparaginase 2 antibody,anti-L asparaginase I antibody, anti-L asparaginase II antibody, anti-L asparaginase IIprecursor antibody, anti-L asparagine amidohydrolase I antibody, anti-L asparagineamidohydrolase II antibody.

Spezifität: Assay by immunoelectrophoresis resulted in a single precipitin arc against anti Biotin,anti Rabbit Serum as well as purified and partially purified Asparaginase (from E. coli). Species Reactivity: Cross-reacts with E. coli.Not yet tested in other species. Localization: Cytoplasmic and Secreted.

Anwendungen

Konzentration: 10 mg/mlBuffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2Stabilizer: 10 mg/ml Bovine Seru. Preservative: 0.01% (w/v) Sodium Azide.

Lagerung: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles.

Forschungsgebiet: Enzyme

Beschränkungen: Nur für Forschungszwecke einsetzbar