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Histone 3 Antikörper (H3K9me3)

H3 Reaktivität: Human WB, IF, ChIP, DB, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2668405
  • Target Alle Histone 3 (H3) Antikörper anzeigen
    Histone 3 (H3)
    Bindungsspezifität
    • 63
    • 47
    • 46
    • 45
    • 41
    • 37
    • 36
    • 35
    • 35
    • 35
    • 34
    • 32
    • 31
    • 29
    • 29
    • 29
    • 26
    • 25
    • 23
    • 23
    • 23
    • 22
    • 20
    • 18
    • 18
    • 17
    • 17
    • 16
    • 16
    • 16
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    • 15
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    • 13
    • 12
    • 12
    • 12
    • 12
    • 12
    • 11
    • 11
    • 10
    • 10
    • 10
    • 9
    • 9
    • 8
    H3K9me3
    Reaktivität
    • 1408
    • 942
    • 862
    • 59
    • 42
    • 41
    • 41
    • 40
    • 39
    • 35
    • 35
    • 30
    • 30
    • 22
    • 19
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 1218
    • 247
    • 12
    • 4
    Kaninchen
    Klonalität
    • 1121
    • 359
    • 1
    Polyklonal
    Konjugat
    • 824
    • 81
    • 65
    • 64
    • 63
    • 63
    • 63
    • 62
    • 37
    • 33
    • 24
    • 17
    • 17
    • 17
    • 17
    • 17
    • 14
    • 2
    • 1
    Dieser Histone 3 Antikörper ist unkonjugiert
    Applikation
    • 1059
    • 411
    • 379
    • 313
    • 252
    • 188
    • 186
    • 179
    • 163
    • 161
    • 142
    • 127
    • 119
    • 48
    • 38
    • 34
    • 32
    • 20
    • 16
    • 14
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP), Dot Blot (DB), Immunocytochemistry (ICC)
    Aufreinigung
    Protein A Chromatography
    Immunogen
    This Histone H3 trimethylLys9 antibody was raised against a peptide including trimethyllysine 9 of histone H3.
    Isotyp
    IgG
    Top Product
    Discover our top product H3 Primärantikörper
  • Applikationshinweise
    Recommended antibody dilutions for different applications:
    ChIP: 10 µg for each ChIP
    ICC/IF: 1 µg/mL dilution
    WB: 0.5 - 2 µg/mL dilution
    CUT&Tag: 1 µg for each 50 µL reaction
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 μg/μL
    Buffer
    Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung

    Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

    Lagerung
    -20 °C
    Informationen zur Lagerung
    Antibodies in solution can be stored at -20 °C for 2 years.
    Haltbarkeit
    6 months
  • Zhang, Li, Rezaeian, Xu, Chou, Jin, Han, Pan, Wang, Long, Zhang, Huang, Tsai, Tsai, Logothetis, Lin: "H3 ubiquitination by NEDD4 regulates H3 acetylation and tumorigenesis." in: Nature communications, Vol. 8, pp. 14799, (2017) (PubMed).

    Maison, Bailly, Quivy, Almouzni: "The methyltransferase Suv39h1 links the SUMO pathway to HP1α marking at pericentric heterochromatin." in: Nature communications, Vol. 7, pp. 12224, (2016) (PubMed).

    Quattrocelli, Swinnen, Giacomazzi, Camps, Barthélemy, Ceccarelli, Caluwé, Grosemans, Thorrez, Pelizzo, Muijtjens, Verfaillie, Blot, Janssens, Sampaolesi: "Mesodermal iPSC-derived progenitor cells functionally regenerate cardiac and skeletal muscle." in: The Journal of clinical investigation, Vol. 125, Issue 12, pp. 4463-82, (2015) (PubMed).

    Lu, Venneti, Akalin, Fang, Ward, Dematteo, Intlekofer, Chen, Ye, Hameed, Nafa, Agaram, Cross, Khanin, Mason, Healey, Lowe, Schwartz, Melnick, Thompson: "Induction of sarcomas by mutant IDH2." in: Genes & development, Vol. 27, Issue 18, pp. 1986-98, (2013) (PubMed).

    Tennakoon, Wang, Coarfa, Cooney, Gunaratne: "Chromatin changes in dicer-deficient mouse embryonic stem cells in response to retinoic acid induced differentiation." in: PLoS ONE, Vol. 8, Issue 9, pp. e74556, (2013) (PubMed).

    Chen, Liu, Lu, Cross, Morris, Shroff, Ward, Bradner, Thompson, Lowe: "Cancer-associated IDH2 mutants drive an acute myeloid leukemia that is susceptible to Brd4 inhibition." in: Genes & development, Vol. 27, Issue 18, pp. 1974-85, (2013) (PubMed).

    Rothbart, Krajewski, Nady, Tempel, Xue, Badeaux, Barsyte-Lovejoy, Martinez, Bedford, Fuchs, Arrowsmith, Strahl: "Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylation." in: Nature structural & molecular biology, Vol. 19, Issue 11, pp. 1155-60, (2012) (PubMed).

  • Target
    Histone 3 (H3)
    Andere Bezeichnung
    Histone H3 (H3 Produkte)
    Synonyme
    H-3 antikoerper, histocompatibility 3 antikoerper, H3 antikoerper
    Molekulargewicht
    17 kDa
    Gen-ID
    3020
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