H2AFX Antikörper (pSer139)

Produktnummer ABIN6579164

Produktdetails anti-H2AFX Antikörper

Target: H2AFX (H2A Histone Family, Member X (H2AFX))

Bindungsspezifität: pSer139

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser H2AFX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Aufreinigung: Protein A Chromatography

Immunogen: This Histone H2AX pSer139 antibody was raised against a peptide including pserine 139 of histone H2AX.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 μg/μL

Buffer: 10 mM sodium phosphate pH 7.5, 150 mM NaCl, 30 % glycerol, 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung:

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Lagerung: -20 °C

Informationen zur Lagerung: Antibodies in solution can be stored at -20 °C for 2 years.

Haltbarkeit: 6 months

Referenzen für anti-H2AFX Antikörper (ABIN6579164)

Velichko, Petrova, Kantidze, Razin: "Dual effect of heat shock on DNA replication and genome integrity." in: Molecular biology of the cell, Vol. 23, Issue 17, pp. 3450-60, (2012) (PubMed).

Hicks, Chute, Paulsen, Ragland, Howlett, Guéranger, Glover, Canman: "Differential roles for DNA polymerases eta, zeta, and REV1 in lesion bypass of intrastrand versus interstrand DNA cross-links." in: Molecular and cellular biology, Vol. 30, Issue 5, pp. 1217-30, (2010) (PubMed).

Li, Corsa, Pan, Wu, Ferguson, Yu, Min, Dou: "MOF and H4 K16 acetylation play important roles in DNA damage repair by modulating recruitment of DNA damage repair protein Mdc1." in: Molecular and cellular biology, Vol. 30, Issue 22, pp. 5335-47, (2010) (PubMed).

Details zu H2AFX

Target: H2AFX (H2A Histone Family, Member X (H2AFX))

Andere Bezeichnung: Histone H2A.X (H2AFX Produkte)

Synonyme: H2A.X antikoerper, H2A/X antikoerper, H2AX antikoerper, AW228881 antikoerper, H2ax antikoerper, Hist5-2ax antikoerper, gammaH2ax antikoerper, zgc:56329 antikoerper, h2a.x antikoerper, h2a/x antikoerper, h2ax antikoerper, RGD1566119 antikoerper, h2a antikoerper, h2afx antikoerper, H2A histone family member X antikoerper, H2A histone family, member X antikoerper, H2A histone family member X L homeolog antikoerper, histone cluster 1, H2ah antikoerper, histone cluster 2, H2ab S homeolog antikoerper, histone H2AX antikoerper, H2AFX antikoerper, H2afx antikoerper, h2afx antikoerper, h2afx.L antikoerper, HIST1H2AH antikoerper, hist2h2ab.S antikoerper, LOC100522201 antikoerper, LOC100720536 antikoerper

Molekulargewicht: 15 kDa

Gen-ID: 92815

Pathways: Telomere Maintenance, DNA Reparatur, Positive Regulation of Response to DNA Damage Stimulus