PARP1 Antikörper (N-Term)

Produktnummer ABIN2668274

Produktdetails anti-PARP1 Antikörper

Target: PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PARP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

Aufreinigung: None

Immunogen: This PARP-1 N-terminal antibody was raised against a His-tagged fusion protein corresponding to the N-terminal half of human PARP-1 was used to generate this PARP-1 antibody.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung:

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Lagerung: -20 °C

Informationen zur Lagerung: Antibodies in solution can be stored at -20 °C for 2 years.

Haltbarkeit: 6 months

Referenzen für anti-PARP1 Antikörper (ABIN2668274)

Myers, Peddada, Chatterjee, Friedrich, Tomoda, Krings, Thomas, Maynard, Broeker, Thomson, Pollard, Yamanaka, Burlingame, Panning: "SOX2 O-GlcNAcylation alters its protein-protein interactions and genomic occupancy to modulate gene expression in pluripotent cells." in: eLife, Vol. 5, pp. e10647, (2016) (PubMed).

Watanabe, Papoutsoglou, Maturi, Tsubakihara, Hottiger, Heldin, Moustakas: "Regulation of Bone Morphogenetic Protein Signaling by ADP-ribosylation." in: The Journal of biological chemistry, Vol. 291, Issue 24, pp. 12706-23, (2016) (PubMed).

Matveeva, Maiorano, Zhang, Eteleeb, Convertini, Chen, Infantino, Stamm, Wang, Rouchka, Fondufe-Mittendorf: "Involvement of PARP1 in the regulation of alternative splicing." in: Cell discovery, Vol. 2, pp. 15046, (2016) (PubMed).

Krishnakumar, Gamble, Frizzell, Berrocal, Kininis, Kraus: "Reciprocal binding of PARP-1 and histone H1 at promoters specifies transcriptional outcomes." in: Science (New York, N.Y.), Vol. 319, Issue 5864, pp. 819-21, (2008) (PubMed).

Kim, Mauro, Gévry, Lis, Kraus: "NAD+-dependent modulation of chromatin structure and transcription by nucleosome binding properties of PARP-1." in: Cell, Vol. 119, Issue 6, pp. 803-14, (2004) (PubMed).

Details zu PARP1

Target: PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

Andere Bezeichnung: PARP-1 (PARP1 Produkte)

Synonyme: ADPRT antikoerper, ADPRT 1 antikoerper, ADPRT1 antikoerper, ARTD1 antikoerper, PARP antikoerper, PARP-1 antikoerper, PPOL antikoerper, pADPRT-1 antikoerper, Adprt antikoerper, Parp-1 antikoerper, 5830444G22Rik antikoerper, AI893648 antikoerper, Adprp antikoerper, Adprt1 antikoerper, C80510 antikoerper, parp-1 antikoerper, sPARP-1 antikoerper, BEST:LD21673 antikoerper, CG17685 antikoerper, CG17696 antikoerper, CG17718 antikoerper, CG40411 antikoerper, D.PARP antikoerper, Dm.pARTa antikoerper, Dmel\\CG40411 antikoerper, LD21673.3prime antikoerper, PARP1 antikoerper, dPARP antikoerper, parp antikoerper, adprt1 antikoerper, padprt-1 antikoerper, ppol antikoerper, si:dkey-206f10.3 antikoerper, wu:fc60f12 antikoerper, zgc:110092 antikoerper, poly(ADP-ribose) polymerase 1 antikoerper, poly (ADP-ribose) polymerase 1 antikoerper, poly (ADP-ribose) polymerase family, member 1 antikoerper, Poly-(ADP-ribose) polymerase antikoerper, poly(ADP-ribose) polymerase 1 L homeolog antikoerper, PARP1 antikoerper, Parp1 antikoerper, Parp antikoerper, parp1.L antikoerper, parp1 antikoerper

Molekulargewicht: 120 kDa

Gen-ID: 142

Pathways: Apoptose, Caspase Kaskade in der Apoptose, DNA Reparatur, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location