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IRF9 Antikörper

IRF9 Reaktivität: Human FACS Wirt: Maus Monoclonal 5A3A39 unconjugated
Produktnummer ABIN2666230
  • Target Alle IRF9 Antikörper anzeigen
    IRF9 (Interferon Regulatory Factor 9 (IRF9))
    Reaktivität
    • 48
    • 16
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 43
    • 6
    • 1
    Maus
    Klonalität
    • 45
    • 4
    Monoklonal
    Konjugat
    • 25
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IRF9 Antikörper ist unkonjugiert
    Applikation
    • 37
    • 15
    • 13
    • 13
    • 10
    • 9
    • 8
    • 3
    • 2
    • 2
    • 2
    Flow Cytometry (FACS)
    Aufreinigung
    Affinity purified.
    Klon
    5A3A39
    Isotyp
    IgG2b kappa
    Top Product
    Discover our top product IRF9 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Upon receipt, store undiluted 2°C and 8°C.
  • Target
    IRF9 (Interferon Regulatory Factor 9 (IRF9))
    Andere Bezeichnung
    IRF9 (IRF9 Produkte)
    Synonyme
    IRF-9 antikoerper, ISGF3 antikoerper, ISGF3G antikoerper, p48 antikoerper, zgc:92097 antikoerper, Irf-9 antikoerper, Isgf3g antikoerper, interferon regulatory factor 9 antikoerper, IRF9 antikoerper, irf9 antikoerper, Irf9 antikoerper
    Hintergrund
    IRF9 is a member of the IRF family of transcription factors and plays an important role in IFN signaling pathways and anti-viral immune responses. Type I and type III interferon stimulation induces phosphorylation and heterodimerization of STAT1 and STAT2. The activated STAT1:STAT2 heterodimer recruits IRF9 and forms a heterotrimeric complex termed IFN-stimulated gene factor 3 (ISGF3). The ISGF3 complex, in turn, translocates to the nucleus and transactivates IFN-inducible genes. The IRF9 protein in the ISGF3 complex is responsible for the recognition of IFN-stimulated response elements (ISRE). Mice lacking IRF9 fail to induce the expression of IFN regulated genes in response to type I interferon stimulation, indicating that IRF9 is crucial in mediating interferon signaling.
    Pathways
    JAK-STAT Signalweg, Interferon-gamma Pathway, Hepatitis C
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