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IL-33 Antikörper (AA 112-270)
IL33
Reaktivität: Human
IHC, FACS
Wirt: Ziege
Polyclonal
Poly5163
unconjugated
Produktnummer ABIN2665497
Produktdetails anti-IL-33 Antikörper
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Target
Alle IL-33 (IL33) Antikörper anzeigen
IL-33 (IL33)
(Interleukin 33 (IL33))
Bindungsspezifität
Alle Epitope für IL-33 Antikörper
AA 112-270
Reaktivität
Alle Reaktivitäten für IL-33 Antikörper
Human
Wirt
Alle Wirte für IL-33 Antikörper
Ziege
Klonalität
Alle Klonalitäten für IL-33 Antikörper
Polyklonal
Konjugat
Alle Konjugate für IL-33 Antikörper
Dieser IL-33 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für IL-33 Antikörper
Immunohistochemistry (IHC), Flow Cytometry (FACS)
Kreuzreaktivität (Details)
In sandwich ELISA, no cross-reactivity with mouse or rat IL-33.
Aufreinigung
The antibody was purified by antigen affinity chromatography.
Immunogen
AA 112-270 (Accession# NM_033439) was expressed in E. coli.
Klon
Poly5163
Isotyp
Ig Fraction, IgG
Top Product
Discover our top product IL33 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Do not freeze.
Lagerung
4 °C
Informationen zur Lagerung
The antibody solution should be stored undiluted between 2°C and 8°C.
Details zu IL-33
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Target
IL-33 (IL33)
(Interleukin 33 (IL33))
Andere Bezeichnung
IL-33 (IL33 Produkte )
Synonyme
IL33 antikoerper, C9orf26 antikoerper, DVS27 antikoerper, IL1F11 antikoerper, NF-HEV antikoerper, NFEHEV antikoerper, RP11-575C20.2 antikoerper, 9230117N10Rik antikoerper, Il-33 antikoerper, Il1f11 antikoerper, RGD1311155 antikoerper, interleukin 33 antikoerper, IL33 antikoerper, Il33 antikoerper
Hintergrund
IL-33, also known as NFHEV and DVS 27, is a 30 kD proinflammatory protein that belongs to IL-1 superfamily. IL-33 is constitutively expressed in smooth muscle and airway epithelia. It is upregulated in arterial smooth muscle, dermal fibroblasts, and keratinocytes following IL-1α or IL-1β stimulation. IL-33 interacts with IL1RL1/ST2 receptor and IL-1 receptor accessory protein (IL1RAP) in order to activate intracellular molecules in the NF-κB and MAP kinase signaling pathways that drive production of type 2 cytokines (e.g. IL-5 and IL-13) from polarized Th2 cells. Recombinant IL-33 has been shown to enhance Th2-associated immune responses and potently increase mast cell proliferation and cytokine production.
Pathways
Production of Molecular Mediator of Immune Response
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