Estrogen Receptor 1 (ESR1) Antikörper

Antigen: Estrogen Receptor 1 (ESR1)

Synonyme: AAC2, PNAT, ACTGP1, ACT1GP1, HY-psi-gamma-AC6, 7B4, CD144, FLJ17376, ER, ESR, Era, ESRA, NR3A1, DKFZp686N23123, ERa, Estr, ER[a], Estra, Nr3a1, ERalpha, AA420328, AU041214, ER-alpha, ER[b], Estrb, ERbeta, Esr, RNESTROR, eralpha, zfER[a], ESR2, ERB, Errra, ERRalpha, ER[b]1, zfER[b]1, MGC103724, zfER-beta1, ER[b]2, ER[b]a, zfER[b]2, zfER-beta2, erb, esrb, estrb, nr3a2, er-beta, esr-beta, XER, era, esr, esra, nr3a1, xesr-1, xlERalpha1, xlERalpha2, CERB, ER-beta, ESR1, LOC398733, LOC398734, ESRRA, ESTRRA, ERBETA, ERALPHA, err1, erra, esrral, erralpha, esrl1, nr3b1, MGC147343, er, LOC100125507

Klonalität: Monoklonal (TE111-5D11)

Wirt: Maus

Reaktivität: Human, Maus, Ratte (Rattus)

Applikation: Elektromobilitäts-Experimente (EMSA), Immunpräzipitation (IP), Western Blot (WB)

Produktnummer: ABIN266502

Produktbeschreibung

Weitere Bezeichnung: Estrogen receptor alpha

Gen-ID: 2099, 13982, 24890

Immunogen: Recombinant fragment, corresponding to amino acids 302-595 of Human EstrogenReceptor.

Isotyp: IgG1  (Passende Sekundärantikörper)

Klon: TE111-5D11

Beschreibung: The estrogen receptor (ER) is a 66 kDa protein that mediates the actions of estrogens inestrogen responsive tissues. It is a member of a large superfamily of nuclear hormonereceptors that function as ligand activated transcription factors. The ER gene consists ofmore than 140 kb of genomic DNA divided into 8 exons. These translate into a proteinwith six functionally discrete domains, labeled A through F. A second form of theestrogen receptor, ER beta has recently been described. The ER is an importantregulator of growth and differentiation in the mammary gland. Presence of ER in breasttumors indicates an increased likelihood of response to anti estrogen (e.g. tamoxifen)therapy. Alternate Names: anti-DKFZp686N23123 antibody, anti-ER Alpha antibody, anti-ER antibody, anti-ERAantibody, anti-ESR 1 antibody, anti-ESR antibody, anti-ESR1 antibody, anti-ESRAantibody, anti-Estradiol Receptor antibody, anti-Estrogen receptor 1 antibody, anti-NR3A1 antibody, anti-NR3A1 antibody.

Spezifität: Species Reactivity: Cross-reacts with Human, Mouse and Rat. Not yet tested in other species. Localization: Nuclear.

Synonyme: AAC2, PNAT, ACTGP1, ACT1GP1, HY-psi-gamma-AC6, 7B4, CD144, FLJ17376, ER, ESR, Era, ESRA, NR3A1, DKFZp686N23123, ERa, Estr, ER[a], Estra, Nr3a1, ERalpha, AA420328, AU041214, ER-alpha, ER[b], Estrb, ERbeta, Esr, RNESTROR, eralpha, zfER[a], ESR2, ERB, Errra, ERRalpha, ER[b]1, zfER[b]1, MGC103724, zfER-beta1, ER[b]2, ER[b]a, zfER[b]2, zfER-beta2, erb, esrb, estrb, nr3a2, er-beta, esr-beta, XER, era, esr, esra, nr3a1, xesr-1, xlERalpha1, xlERalpha2, CERB, ER-beta, ESR1, LOC398733, LOC398734, ESRRA, ESTRRA, ERBETA, ERALPHA, err1, erra, esrral, erralpha, esrl1, nr3b1, MGC147343, er, LOC100125507

Anwendungen

Applikationshinweise: Positive Controls: MCF-7 cells.

Konzentration: 1 mg/ml

Buffer: PBS. Preservative: 0.08% Sodium Azide

Lagerung: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles.

Forschungsgebiet: Hormone, Rezeptoren

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

anti-Estrogen Receptor 1 (ESR1) antibody