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Chemokine (C-C Motif) Receptor 3 (CCR3) Antikörper
| Antigen | Chemokine (C-C Motif) Receptor 3 (CCR3) |
| Synonyme | CKR3, CD193, CMKBR3, CC-CKR-3, MGC102841 |
| Klonalität | Monoklonal (5E8) |
| Wirt |
 Alternativen Maus |
| Applikation |
Alternativen Durchflusszytometrie (FACS), Immunfluoreszenz (IF)
|
| Produktnummer | ABIN266491 |
| Menge | 0.1 mg (1 mg/ml) |
| Preis | 370,00 € Zzgl. Versandkosten €20,00 und MWSt |
| Lieferung nach |
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| Verfügbarkeit | Lieferung in 7 bis 10 Werktagen |
Produktbeschreibung
| Weitere Bezeichnung | CD193 / CCR3 |
| Gen-ID | 1232 |
| Immunogen | Tissue / cell preparation (Human) - human CCR3 transfected into mouse B celllymphoma L1.2 cells. |
| Isotyp | IgG2a (Passende Sekundärantikörper) |
| Klon | 5E8 |
| Beschreibung | CCR3 is a receptor for CC chemokine eotaxin 1 and eotaxin 2. CCR3 has been reportedin blood, brain, lung, bone marrow, kidney, liver, lymph node, placenta, skin, spleen,thymus, thyroid, uterus, and vessel. Within these tissues, CCR3 is expressed in specificcell types, including eosinophils, basophils, Th2 cells, and mast cells. The agonists forCXCR3 (IP-10, mig, and I-TAC) act as antagonists for CCR3 by competing for thebinding of eotaxin to CCR3. The 356 amino acid CCR3 receptor is expressed on humaneosinophils, basophils, neutrophils, mast cells, mononuclear phagocytes, platelets,CD34+ hematopoietic progenitor cells, Th2 like lymphocytes, and keratinocytes. CCR3is thought to play a key role in allergic diseases such as bronchial asthma and allergicrhinitis. CCR3 is a co-receptor for HIV 1 and 2 and the binding of eotaxin with CCR3 hasbeen shown to inhibit HIV infection in some cell types. The CCR3 receptor has beenreported to be upregulated by high affinity Fc IgE receptor ligation. Alternate Names: anti-B Chemokine Receptor antibody, anti-C C chemokine receptor type 3 antibody,anti-C C CKR 3 antibody, anti-CC Chemokine Receptor 3 antibody, anti-CC chemokinereceptor type 3 antibody, anti-CC CKR 3 antibody, anti-CC R3 antibody, anti-CCCKR3antibody, anti-CCR 3 antibody, anti-CD 193 antibody, anti-CD193 antibody, anti-CD193antigen antibody, anti-Chemokine (C C motif) receptor 3 antibody, anti-Chemokine (CC)Receptor 1 Like 2 antibody, anti-Chemokine CC Motif Receptor 3 antibody,anti-Chemokine receptor 3 antibody, anti-CK R3 antibody, anti-CKR 3 antibody,anti-CKR3 antibody, anti-CMKB R3 antibody, anti-CMKBR 3 antibody, anti-CMKBR1L2antibody, anti-CMKBR3 antibody, anti-Eosinophil CC Chemokine Receptor 3 antibody,anti-Eosinophil Eotaxin Receptor antibody, anti-Eotaxin Receptor antibody,anti-Macrophage Inflammatory Protein1 Alpha Receptor Like 2 antibody,anti-MGC102841 antibody, anti-MIP1 Alpha RL2 antibody. |
| Spezifität | Species Reactivity: Cross-reacts with Human.Not yet tested in other species. Localization: Integral membrane protein. |
Anwendungen
| Applikationshinweise | Positive Controls: Blood eosinophils and basophils. |
| Konzentration | 1 mg/ml |
| Buffer | Phosphate-buffered solution, pH 7.2. Preservative: 0.09% Sodium Azide (NaN3). |
| Lagerung | The antibody solution should be stored undiluted at 4Degree C. |
| Forschungsgebiet | Chemokine, Rezeptoren, CD Antigene |
| Beschränkungen | Nur für Forschungszwecke einsetzbar |
Alternativen
Alternativen zu Antigen "Chemokine (C-C Motif) Receptor 3 (CCR3)", Typ "Antikörper" finden
| Wirte | Kaninchen (20), Maus (4), Ziege (3), Ratte (2) |
| Reaktivitäten | Human (26), Maus (9), Ratte (Rattus) (4) |
| Applikationen | Western Blot (WB) (15), Immunhistochemie (Paraffinschnitte) (IHC (p)) (13), Enzyme Immunoassay (EIA) (7), Durchflusszytometrie (FACS) (7), Immunfluoreszenz (IF) (4), Immunhistochemie (IHC) (3), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (2), Dot Blot (Dot) (1), Neutralisierung (Neut) (1) |
| Konjugate | Alexa Fluor 647 (3), APC (2), PerCP,Cy5.5 (1) |
| Epitope | C-Term (3), N-Term (2) |
