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LILRB1 Antikörper
LILRB1
Reaktivität: Human
MA
Wirt: Maus
Monoclonal
GHI-75
unconjugated
Produktnummer ABIN2664844
Produktdetails anti-LILRB1 Antikörper
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Target
Alle LILRB1 Antikörper anzeigen
LILRB1
(Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 1 (LILRB1))
Reaktivität
Alle Reaktivitäten für LILRB1 Antikörper
Human
Wirt
Alle Wirte für LILRB1 Antikörper
Maus
Klonalität
Alle Klonalitäten für LILRB1 Antikörper
Monoklonal
Konjugat
Alle Konjugate für LILRB1 Antikörper
Dieser LILRB1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für LILRB1 Antikörper
Multiplex Assay (MA)
Aufreinigung
The antibody was purified by affinity chromatography.
Klon
GHI-75
Isotyp
IgG2b kappa
Top Product
Discover our top product LILRB1 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Informationen zur Lagerung
The antibody solution should be stored undiluted between 2°C and 8°C.
Details zu LILRB1
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Target
LILRB1
(Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 1 (LILRB1))
Andere Bezeichnung
CD85j (LILRB1 Produkte )
Synonyme
CD85J antikoerper, ILT-2 antikoerper, ILT2 antikoerper, LIR-1 antikoerper, LIR1 antikoerper, MIR-7 antikoerper, MIR7 antikoerper, leukocyte immunoglobulin like receptor B1 antikoerper, LILRB1 antikoerper
Hintergrund
CD85 is a group of Ig superfamily tansmembrane glycoproteins called Ig-Like Transcripts (ILTs) or Leukocyte Immunoglobulin-like Receptors (LIRs). CD85j is the 110kD member, known as ILT2, LIR1, or LILRB1, and MIR7. ILT2 structurally has four Ig domains and contains ITIMs in its cytoplasmic tail that provide inhibitory signals by recruiting SHP-1. ILT2 is found on the surface of B cells, plasma cells, dendritic cells, monocytes, subsets of NK and T cells. The ligands of ILT2 include a broad range of HLA-A, -B molecules, some HLA-C and HLA-G molecules, and the human cytomegalovirus UL18 protein.
Pathways
Cellular Response to Molecule of Bacterial Origin , Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Production of Molecular Mediator of Immune Response
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