CCR5 Antikörper (Pacific Blue)

Produktnummer ABIN2662213

Produktdetails anti-CCR5 Antikörper (Pacific Blue)

Target: CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

Reaktivität: Human

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser CCR5 Antikörper ist konjugiert mit Pacific Blue

Applikation: Immunoprecipitation (IP), Purification (Purif)

Aufreinigung: The antibody was purified by affinity chromatography, and conjugated with Pacific Blue™ under optimal conditions. The solution is free of unconjugated Pacific Blue™.

Klon: HEK-1-85a

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu CCR5

Target: CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

Andere Bezeichnung: CD195 (CCR5 Produkte)

Synonyme: CC-CKR-5 antikoerper, CCCKR5 antikoerper, CCR-5 antikoerper, CD195 antikoerper, CKR-5 antikoerper, CKR5 antikoerper, CMKBR5 antikoerper, IDDM22 antikoerper, Ckr5 antikoerper, Cmkbr5 antikoerper, CCR1-L antikoerper, GPCR antikoerper, CCR5 antikoerper, AM4-7 antikoerper, C-C motif chemokine receptor 5 (gene/pseudogene) antikoerper, chemokine (C-C motif) receptor 5 antikoerper, C-C motif chemokine receptor 5 antikoerper, CCR5 antikoerper, Ccr5 antikoerper

Hintergrund: CD195, also known as CCR5, is a 45 kD G protein-coupled seven transmembrane CC-chemokine receptor. It binds to MIP-1α, MIP-1β, and RANTES and is expressed on a subset of T cells and monocytes. CD195 mediates an intracellular signal thought to induce cell differentiation and proliferation. CCR5 has also been shown to act as a co-receptor for R5 HIV-1 cell entry, modification of CCR5 by sulfation contributes to the efficiency of HIV-1 entry. Recent studies have shown CCR5 to play a role in a variety of other human diseases, ranging from infectious and inflammatory diseases to cancer.

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size