Heat Shock Protein 90 alpha/beta (HSP90 alpha/beta) Antikörper

Antigen: Heat Shock Protein 90 alpha/beta (HSP90 alpha/beta)

Klonalität: Monoklonal (S88)

Wirt: Maus

Reaktivität: Meerschweinchen, Human, Affe, Maus, Kaninchen, Ratte (Rattus), Schaf

Applikation: Immunhistochemie (Gefrierschnitte) (IHC (fro)), Immunpräzipitation (IP), Western Blot (WB)

Produktnummer: ABIN266159

Produktbeschreibung

Weitere Bezeichnung: Heat Shock Protein 90 / HSP90 (alpha + beta)

Gen-ID: 3320, 15516, 301252

Immunogen: Full length native protein (purified) (Achlya ambisexualis).

Format: Serum

Isotyp: IgG1  (Passende Sekundärantikörper)

Klon: S88

Beschreibung: In mammalian cells there are at least two Hsp90 isoforms, Hsp90a and Hsp90b whichare encoded by separate genes. These ubiquitous and highly conserved proteinsaccount for 1-2% of all cellular proteins in most cells. Hsp90 is part of the cells powerfulnetwork of chaperones to fight the deleterious consequences of protein unfoldingcaused by nonphysiological conditions. However, in the absence of stress, Hsp90 is anecessary component of fundamental cellular processes such as hormone signaling andcell cycle control. In this context several key regulatory proteins such as steriodreceptors, cell cycle kinases involved in signal transduction and p53 have beenidentified as substrates of Hsp90. It has been suggested that Hsp90 acts as a capacitorfor morphological evolution by buffering widespread variation, which may affectmorphogenic pathways. Alternate Names: anti-D6S182 antibody, anti-FLJ26984 antibody, anti-FLJ31884 antibody, anti-heat shock90kDa protein 1 alpha antibody, anti-Heat shock protein 90kDa alpha cytosolic class Amember 1 antibody, anti-Heat shock protein 90kDa alpha cytosolic class B member 1antibody, anti-Heat shock protein HSP 90 alpha antibody, anti-Heat shock protein HSP90 beta antibody, anti-HSP 84 antibody, anti-HSP 86 antibody, anti-Hsp 90 antibody,anti-HSP84 antibody, anti-HSP86 antibody, anti-Hsp89 antibody, anti-Hsp90 antibody,anti-HSP90 Beta antibody, anti-HSP90A antibody, anti-HSP90AA1 antibody,anti-HSP90AB1 antibody, anti-HSP90B antibody, anti-HSP90N antibody, anti-HSPC1antibody, anti-HSPC2 antibody, anti-HSPCA antibody, anti-HSPCAL1 antibody,anti-HSPCAL4 antibody, anti-HSPCB antibody, anti-HSPN antibody, anti-LAP2antibody, anti-Lipopolysaccharide associated protein2 antibody, anti-LPS associatedprotein 2 antibody, anti-NY REN 38 antigen antibody.

Spezifität: The antibody recognizes a 90 kDa protein, corresponding to the apparent molecularweight of Hsp90 on SDS-PAGE immunoblots. This antibody detects both Hsp90 alphaand beta. Species Reactivity: Cross-reacts with Chicken, Cow, Dog, Guinea Pig, Human, Mouse, Pig, Rabbit, Rat,Sheep and Monkey. Not yet tested in other species. Localization: Cytoplasmic.

Anwendungen

Applikationshinweise: Suggested working dilutions: immunoprecipitation 4 ug/ml,Western Blot 1 ug/ml,Immunohistochemistry-Frozen 10 - 20 ug/ml

Konzentration: 0.2 mg/ml

Buffer: PBS pH7.2 with 50% glycerol, 1% BSA. Preservative: Thimerosal.

Lagerung: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

anti-Heat Shock Protein 90 alpha/beta (HSP90 alpha/beta) antibody