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IL-33 Antikörper (AA 112-270) (Biotin)

IL33 Reaktivität: Human FACS Wirt: Ziege Polyclonal Poly5163 Biotin
Produktnummer ABIN2661328
  • Target Alle IL-33 (IL33) Antikörper anzeigen
    IL-33 (IL33) (Interleukin 33 (IL33))
    Bindungsspezifität
    • 20
    • 16
    • 10
    • 9
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 112-270
    Reaktivität
    • 82
    • 48
    • 39
    • 9
    • 1
    Human
    Wirt
    • 102
    • 27
    • 7
    • 3
    • 2
    • 1
    • 1
    Ziege
    Klonalität
    • 113
    • 30
    Polyklonal
    Konjugat
    • 73
    • 22
    • 13
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IL-33 Antikörper ist konjugiert mit Biotin
    Applikation
    • 85
    • 68
    • 36
    • 28
    • 19
    • 15
    • 14
    • 14
    • 13
    • 11
    • 9
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    Flow Cytometry (FACS)
    Kreuzreaktivität (Details)
    In sandwich ELISA, no cross-reactivity with mouse or rat IL-33.
    Aufreinigung
    The antibody was purified by antigen affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
    Immunogen
    AA 112-270 (Accession# NM_033439) was expressed in E. coli.
    Klon
    Poly5163
    Isotyp
    Ig Fraction, IgG
    Top Product
    Discover our top product IL33 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.2 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 1 % BSA and 0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Do not freeze.
    Lagerung
    4 °C
    Informationen zur Lagerung
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    IL-33 (IL33) (Interleukin 33 (IL33))
    Andere Bezeichnung
    IL-33 (IL33 Produkte)
    Synonyme
    IL33 antikoerper, C9orf26 antikoerper, DVS27 antikoerper, IL1F11 antikoerper, NF-HEV antikoerper, NFEHEV antikoerper, RP11-575C20.2 antikoerper, 9230117N10Rik antikoerper, Il-33 antikoerper, Il1f11 antikoerper, RGD1311155 antikoerper, interleukin 33 antikoerper, IL33 antikoerper, Il33 antikoerper
    Hintergrund
    IL-33, also known as NFHEV and DVS 27, is a 30 kD proinflammatory protein that belongs to IL-1 superfamily. IL-33 is constitutively expressed in smooth muscle and airway epithelia. It is upregulated in arterial smooth muscle, dermal fibroblasts, and keratinocytes following IL-1α or IL-1β stimulation. IL-33 interacts with IL1RL1/ST2 receptor and IL-1 receptor accessory protein (IL1RAP) in order to activate intracellular molecules in the NF-κB and MAP kinase signaling pathways that drive production of type 2 cytokines (e.g. IL-5 and IL-13) from polarized Th2 cells. Recombinant IL-33 has been shown to enhance Th2-associated immune responses and potently increase mast cell proliferation and cytokine production.
    Pathways
    Production of Molecular Mediator of Immune Response
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