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KLRG1 Antikörper (PE-Cy7)

KLRG1 Reaktivität: Maus, Human FACS Wirt: Golden Syrian Hamster Monoclonal 2F1-KLRG1 PE-Cy7
Produktnummer ABIN2659381
  • Target Alle KLRG1 Antikörper anzeigen
    KLRG1 (Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1))
    Reaktivität
    • 33
    • 25
    • 2
    Maus, Human
    Wirt
    • 17
    • 13
    • 11
    • 9
    • 1
    Golden Syrian Hamster
    Klonalität
    • 35
    • 16
    Monoklonal
    Konjugat
    • 20
    • 7
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KLRG1 Antikörper ist konjugiert mit PE-Cy7
    Applikation
    • 34
    • 14
    • 9
    • 7
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Aufreinigung
    The antibody was purified by affinity chromatography and conjugated with PE/Cy7 under optimal conditions. The solution is free of unconjugated PE/Cy7 and unconjugated antibody.
    Klon
    2F1-KLRG1
    Isotyp
    IgG
    Top Product
    Discover our top product KLRG1 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.2 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Protect from prolonged exposure to light. Do not freeze.
    Lagerung
    4 °C
    Informationen zur Lagerung
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    KLRG1 (Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1))
    Andere Bezeichnung
    KLRG1 (KLRG1 Produkte)
    Synonyme
    KLRG1 antikoerper, 2F1-Ag antikoerper, MAFA antikoerper, MAFA-L antikoerper, 2F1 antikoerper, CLEC15A antikoerper, MAFA-2F1 antikoerper, MAFA-LIKE antikoerper, killer cell lectin like receptor G1 antikoerper, killer cell lectin-like receptor subfamily G, member 1 antikoerper, KLRG1 antikoerper, Klrg1 antikoerper
    Hintergrund
    Killer cell lectin-like receptor G1 (KLRG1) is the mouse homolog of the rat mast cell function-associated antigen (MAFA or 2F1-Ag). KLRG1 is a type II membrane glycoprotein that was first identified on the surface of rat mast cell line RBL-2H3. It is composed of a homodimer of glycosylated 30-38 kD subunits. Mouse and human homologs of KLRG1 are expressed by subsets of NK cells and lymphokine-activated killer (LAK) cells but not mast cells. KLRG1 is also expressed on subsets of CD8+ and CD4+ cells, including CD4+ and CD8+ effector/memory cells, potent regulatory CD4+ T cells. KLRG1 may be involved in regulating NK cell homeostasis. KLRG1 was found to recognize cadherins and thus inhibit immune responses by regulating the effector function and the developmental processes of NK and T cells.
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