Angiogenin, Ribonuclease, RNase A Family, 5 (ANG) Antikörper

Antigen: Angiogenin, Ribonuclease, RNase A Family, 5 (ANG)

Synonyme: ALS9, HEL168, RNASE4, RNASE5, MGC22466, MGC71966, ANG1

Klonalität: Monoklonal (14017-7)

Wirt: Maus

Reaktivität: Human

Applikation: Enzyme Immunoassay (EIA), Western Blot (WB)

Produktnummer: ABIN265794

Produktbeschreibung

Weitere Bezeichnung: Angiogenin

Gen-ID: 283

Immunogen: purified recombinant human angiogenin expressed in E. coli.

Isotyp: IgG1  (Passende Sekundärantikörper)

Klon: 14017-7

Beschreibung: Angiogenin is a member of the ribonuclease superfamily with approximately 35% aminoacid sequence identity with pancreatic RNase. Like other members of the ribonucleasesuperfamily, angiogenin is a cytotoxic agent that can eliminate cellular protein synthesis.Angiogenin causes protein synthesis inhibition by functioning as a cytotoxictRNA-specific RNase. Angiogenesis is the formation of blood vessels or capillaries fromexisting blood vessels due to specific signals. Angiogenin induces the growth of newblood vessels. It stimulates capillary and umbilical vein endothelial cells to producediacylglycerol and secrete prostacyclin by phospholipase activation. Angiogenin exhibitsboth angiogenic and non-angiogenic activities and is involved in endothelial cellmigration, proliferation, and differentiation. It is produced by a variety of tumor andnormal cell types. Cells that express angiogenin include vascular endothelial andsmooth muscle cells, fibroblasts, normal colonic epithelium, normal peripheral bloodlymphocytes, lung and colonic epithelial tumor cell lines, and primary gastrointestinaladenocarcinomas. Angiogenin is also present in normal human plasma. Alternate Names: anti-AMYOTROPHIC LATERAL SCLEROSIS antibody, anti-ANG 1 antibody, anti-ANGantibody, anti-ANG I antibody, anti-ANG1 antibody, anti-ANGI antibody,anti-Ribonuclease RNase A Family 5 antibody, anti-RNASE 5 antibody, anti-RNASE5antibody.

Spezifität: Species Reactivity: Cross-reacts with Human.Not yet tested in other species. Localization: Secreted.

Anwendungen

Applikationshinweise: ELISA: Use at a concentration of 1 - 2 ug/ml. WB: Use at a concentration of 1 - 2 ug/ml.Detects a band of approximately 14.4 kDa.

Konzentration: 0.5 mg/ml

Buffer: Preservative: NoneConstituents: PBS. Preservative: NoneConstituents: PBS.

Lagerung: Store at +4Degree C short term (1-2 weeks). Aliquot and store at -20Degree C or-80Degree C. Avoid repeated freeze / thaw cycles.

Forschungsgebiet: Zytokine

Beschränkungen: Nur für Forschungszwecke einsetzbar