HSV ICP27 Antikörper

Produktnummer ABIN265583

Produktdetails anti-HSV ICP27 Antikörper

Target: HSV ICP27 (Herpes Simplex Virus ICP27 (HSV ICP27))

Reaktivität: Herpes Simplex Virus (HSV)

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HSV ICP27 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktmerkmale: Mouse monoclonal antibody to ICP27 of Herpes Simplex Virus. This antibody originates from ascites fluids and is purified by protein G agarose affinity chromatography.

Aufreinigung: Protein G agarose affinity chromatography

Klon: H1113

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Reactive with ICP27 of Herpes Simplex Virus in immunofluorescence (IFA) and western blot at 10 ug/ml.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/ml

Buffer: Phosphate Buffered Saline pH 7.4 (no azide)

Konservierungsmittel: Azide free

Lagerung: -20 °C

Referenzen für anti-HSV ICP27 Antikörper (ABIN265583)

Park, Lengyel, Rice: "The role of immediate-early protein ICP27 in the differential sensitivity of herpes simplex viruses type-1 and type-2 to leptomycin B." in: Journal of virology, (2013) (PubMed).

Malik, Tabarraei, Kehlenbach, Korfali, Iwasawa, Graham, Schirmer: "Herpes simplex virus ICP27 protein directly interacts with the nuclear pore complex through Nup62, inhibiting host nucleocytoplasmic transport pathways." in: The Journal of biological chemistry, Vol. 287, Issue 15, pp. 12277-92, (2012) (PubMed).

Jurak, Silverstein, Sharma, Coen: "Herpes Simplex Virus Is Equipped with RNA- and Protein-Based Mechanisms To Repress Expression of ATRX, an Effector of Intrinsic Immunity." in: Journal of virology, Vol. 86, Issue 18, pp. 10093-102, (2012) (PubMed).

Jin, Yan, Ma, Cao, He: "An Herpesvirus Virulence Factor Inhibits Dendritic Cell Maturation Through Protein Phosphatase 1 and I{kappa}B Kinase." in: Journal of virology, (2011) (PubMed).

Luganini, Nicoletto, Pizzuto, Pirri, Giuliani, Landolfo, Gribaudo: "Inhibition of herpes simplex virus type 1 and type 2 infections by peptide-derivatized dendrimers." in: Antimicrobial agents and chemotherapy, Vol. 55, Issue 7, pp. 3231-9, (2011) (PubMed).

Salaun, MacDonald, Larralde, Howard, Lochtie, Burgess, Brook, Malik, Gray, Graham: "Poly(A)-binding protein 1 partially relocalizes to the nucleus during herpes simplex virus type 1 infection in an ICP27-independent manner and does not inhibit virus replication." in: Journal of virology, Vol. 84, Issue 17, pp. 8539-48, (2010) (PubMed).

Details zu HSV ICP27

Target: HSV ICP27 (Herpes Simplex Virus ICP27 (HSV ICP27))

Abstract: HSV ICP27 Produkte

Substanzklasse: Viral Protein

Hintergrund: Herpes simplex virus (HSV) ICP27 (Infected cell polypeptide 27) is an essential and multifunctional regulator of viral gene expression that modulates RNA splicing,polyadenylation, and nuclear export. ICP27 Belongs to the herpes viruses UL69 family. It is involved in the down-regulation of viral immediate-early genes and acts incombination with ICP0 and ICP4 as an activator of late genes. Alternate Names: anti-Herpes simplex virus 1 ICP27 antibody, anti-Herpes simplex virus 1 transcriptional regulator IE63 antibody, anti-Herpes simplex virus 2 ICP27 antibody, anti-Herpessimplex virus 2 transcriptional regulator IE63 antibody