UL84 (CMV UL84) Antikörper

Produktnummer ABIN265546

Produktdetails

Target: UL84 (CMV UL84)

Reaktivität: Cytomegalovirus (CMV)

Wirt: Maus

Klonalität: Monoklonal

Applikation: Immunofluorescence (IF), Western Blotting (WB)

Aufreinigung: Protein G agarose affinity chromatography

Klon: MAB84

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Reactive with pUL84 of Cytomegalovirus in immunofluorescence (IFA) and western blot assays at 10 µg/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/ml

Buffer: Phosphate Buffered Saline pH 7.4 (no azide)

Konservierungsmittel: Azide free

Lagerung: -20 °C

Referenzen

Kim, Ahn: "Role of the specific interaction of UL112-113 p84 with UL44 DNA polymerase processivity factor in promoting DNA replication of human cytomegalovirus." in: Journal of virology, (2010) (PubMed).

Sanders, Clark, Morello, Spector: "Development of cell lines that provide tightly controlled temporal translation of the human cytomegalovirus IE2 proteins for complementation and functional analyses of growth-impaired and nonviable IE2 mutant viruses." in: Journal of virology, Vol. 82, Issue 14, pp. 7059-77, (2008) (PubMed).

Sanders, Del Rosario, White, Spector: "Internal deletions of IE2 86 and loss of the late IE2 60 and IE2 40 proteins encoded by human cytomegalovirus affect the levels of UL84 protein but not the amount of UL84 mRNA or the loading and distribution of the mRNA on polysomes." in: Journal of virology, Vol. 82, Issue 22, pp. 11383-97, (2008) (PubMed).

Colletti, Smallenburg, Xu, Pari: "Human cytomegalovirus UL84 interacts with an RNA stem-loop sequence found within the RNA/DNA hybrid region of oriLyt." in: Journal of virology, Vol. 81, Issue 13, pp. 7077-85, (2007) (PubMed).

Gao, Colletti, Pari: "Identification of human cytomegalovirus UL84 virus- and cell-encoded binding partners by using proteomics analysis." in: Journal of virology, Vol. 82, Issue 1, pp. 96-104, (2007) (PubMed).

White, Del Rosario, Sanders, Spector: "The IE2 60-kilodalton and 40-kilodalton proteins are dispensable for human cytomegalovirus replication but are required for efficient delayed early and late gene expression and production of infectious virus." in: Journal of virology, Vol. 81, Issue 6, pp. 2573-83, (2007) (PubMed).

Colletti, Xu, Cei, Tarrant, Pari: "Human cytomegalovirus UL84 oligomerization and heterodimerization domains act as transdominant inhibitors of oriLyt-dependent DNA replication: evidence that IE2-UL84 and UL84-UL84 interactions are required for lytic DNA replication." in: Journal of virology, Vol. 78, Issue 17, pp. 9203-14, (2004) (PubMed).

Antigendetails

Target: UL84 (CMV UL84)

Substanzklasse: Viral Protein

Hintergrund: Mouse monoclonal antibody to UL84 of Cytomegalovirus. This antibody originates from ascites fluids and is purified by protein G agarose affinity chromatography