PTGS1 Antikörper (pSer585)

Produktnummer ABIN265370

Produktdetails anti-PTGS1 Antikörper

Target: PTGS1 (Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1))

Bindungsspezifität: pSer585

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTGS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of Cox1/PGHS1 protein (region surrounding Ser585).

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen

Reinheit: > 95 % pure by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PTGS1

Target: PTGS1 (Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1))

Andere Bezeichnung: Cyclooxygenase 1 (PTGS1 Produkte)

Synonyme: COX-1 antikoerper, cox-1 antikoerper, PTGS1 antikoerper, Ptgs1 antikoerper, COX1 antikoerper, Cox-1 antikoerper, Cox-3 antikoerper, PGHS-1 antikoerper, PHS 1 antikoerper, Pghs1 antikoerper, Cox1 antikoerper, Cox3 antikoerper, cox1 antikoerper, zCOX-1 antikoerper, COX3 antikoerper, PCOX1 antikoerper, PES-1 antikoerper, PGG/HS antikoerper, PGHS1 antikoerper, PHS1 antikoerper, PTGHS antikoerper, COX-3 antikoerper, prostaglandin-endoperoxide synthase 1 antikoerper, cyclooxygenase-1 antikoerper, prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) antikoerper, prostaglandin-endoperoxide synthase 1 S homeolog antikoerper, PTGS1 antikoerper, cox-1 antikoerper, Ptgs1 antikoerper, ptgs1 antikoerper, ptgs1.S antikoerper

Hintergrund: Cytochrome c oxidase subunit I, COX1 (also designated COI, MTCO2 or oxidative phosphorylation (OxPhos) Complex IV, subunit I) is one of three mitochondrial DNA (mtDNA) encoded subunits (MTCO1-3) of respiratory Complex IV. Cytochrome c oxidase is a hetero-oligomeric enzyme composed of 13 subunits localized to the mitochondrial inner membrane and is the terminal enzyme complex of the electron transport chain. Complex IV catalyzes the reduction of molecular oxygen to water. The energy released is used to transport protons across the mitochondrial inner membrane. The resulting electrochemical gradient is necessary for the synthesis of ATP. Complex IV contains 13 polypeptides, COX1, COX2 and COX3 (MTCO1-3) make up the catalytic core and are encoded by mtDNA while subunits IV, Va, Vb, VIa, VIb, VIc, VIIa, VIIb, VIIc and VIII are nuclear-encoded.Synonyms: COX-1, COX1, Cyclooxygenase-1, PGH synthase 1, PGHS-1, PTGS1, Prostaglandin G/H synthase 1, Prostaglandin H2 synthase 1, Prostaglandin-endoperoxide synthase 1

Molekulargewicht: approx. 70 kDa

Gen-ID: 5742

NCBI Accession: NP_000953

UniProt: P23219