ROBO1 Antikörper

Produktnummer ABIN265227

Produktdetails anti-ROBO1 Antikörper

Target: ROBO1 (Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ROBO1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody detects Roundabout homolog 1 / ROBO1, widely expressed, with exception of kidney.

Aufreinigung: Purified

Immunogen: Synthetic peptide derived from human ROBO1 protein

Anwendungsinformationen

Applikationshinweise: Western Blot (1-5 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.

Details zu ROBO1

Target: ROBO1 (Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1))

Andere Bezeichnung: ROBO1 (ROBO1 Produkte)

Synonyme: DUTT1 antikoerper, SAX3 antikoerper, AW494633 antikoerper, AW742721 antikoerper, Gm310 antikoerper, ROBO1 antikoerper, dutt1 antikoerper, roundabout antikoerper, sax3 antikoerper, MGC122264 antikoerper, roundabout-1 antikoerper, roundabout guidance receptor 1 antikoerper, roundabout, axon guidance receptor, homolog 1 (Drosophila) antikoerper, roundabout guidance receptor 1 L homeolog antikoerper, ROBO1 antikoerper, Robo1 antikoerper, robo1 antikoerper, robo1.L antikoerper

Hintergrund: Receptor for SLIT1 and SLIT2 which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development. In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex. May be required for lung development. Defects in ROBO1 may be a cause of breast and lung cancer. ROBO1 maps within a region of overlapping homozygous deletions characterized in both small cell lung cancer cell lines (SCLC) and in a breast cancer cell line.Synonyms: DUTT1, Deleted in U Twenty Twenty, ROBO-1, Roundabout homolog 1

Gen-ID: 6091

NCBI Accession: NP_002932

UniProt: Q9Y6N7

Pathways: Positive Regulation of Endopeptidase Activity