Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

TOLLIP Antikörper (Middle Region)

TOLLIP Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN265154
  • Target Alle TOLLIP Antikörper anzeigen
    TOLLIP (Toll Interacting Protein (TOLLIP))
    Bindungsspezifität
    • 15
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 41
    • 30
    • 20
    • 17
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 46
    • 11
    • 1
    Kaninchen
    Klonalität
    • 49
    • 10
    Polyklonal
    Konjugat
    • 34
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TOLLIP Antikörper ist unkonjugiert
    Applikation
    • 31
    • 18
    • 13
    • 13
    • 12
    • 8
    • 8
    • 7
    • 6
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Spezifität
    This antibody detects TOLIP. TOLLIP is located in the cytoplasm and phosphorylated by IRAK1 upon stimulation by IL-1 or microbial products (5).
    Aufreinigung
    Purified
    Immunogen
    A 16 amino acid peptide from near the center of human TOLLIP
    Isotyp
    IgG
    Top Product
    Discover our top product TOLLIP Primärantikörper
  • Applikationshinweise
    Western Blot: 1 μg/mL. Positive Control: Rat Brain Lysate. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Phosphate buffered saline with 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store the antibody (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.
  • Target
    TOLLIP (Toll Interacting Protein (TOLLIP))
    Andere Bezeichnung
    TOLLIP (TOLLIP Produkte)
    Synonyme
    IL-1RAcPIP antikoerper, 4930403G24Rik antikoerper, 4931428G15Rik antikoerper, fk22a02 antikoerper, im:7145391 antikoerper, wu:fk22a02 antikoerper, zgc:76985 antikoerper, TOLLIP antikoerper, GB17961 antikoerper, tollip antikoerper, tollip1 antikoerper, tollipa antikoerper, TOLIP antikoerper, toll interacting protein antikoerper, toll-interacting protein antikoerper, toll-interacting protein-like antikoerper, toll interacting protein L homeolog antikoerper, toll interacting protein S homeolog antikoerper, Toll-interleukine I receptor interacting protein I antikoerper, TOLLIP antikoerper, Tollip antikoerper, tollip antikoerper, LOC552034 antikoerper, LOC100169858 antikoerper, tollip.L antikoerper, tollip.S antikoerper, LOC100136122 antikoerper
    Hintergrund
    Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1,2). The TLRs act through adaptor molecules to activate various kinases and transcription factors (3) so the organism can respond to potential infection. These adaptor molecules include TOLLIP, MyD88, and TRIF. TOLLIP associates directly with TLR2 and TLR 4, acting as an inhibitor to TLR activation (4). This negative regulation of TLR signaling may serve to limit the production of proinflammatory mediators during infection and inflammation.Synonyms: Toll-interacting protein
    Gen-ID
    54472
    NCBI Accession
    NP_061882
    UniProt
    Q9H0E2
Sie sind hier:
Kundenservice