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MAPKBP1 Antikörper

MAPKBP1 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2650930
  • Target Alle MAPKBP1 Antikörper anzeigen
    MAPKBP1 (Mitogen-Activated Protein Kinase Binding Protein 1 (MAPKBP1))
    Reaktivität
    • 8
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 7
    • 1
    Kaninchen
    Klonalität
    • 8
    Polyklonal
    Konjugat
    • 8
    Dieser MAPKBP1 Antikörper ist unkonjugiert
    Applikation
    • 7
    • 4
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC)
    Aufreinigung
    Affinity purification
    Immunogen
    A synthetic peptide of human MAPKBP1
    Isotyp
    IgG
    Top Product
    Discover our top product MAPKBP1 Primärantikörper
  • Applikationshinweise
    WB 1:200 - 1:500
    IHC 1:50 - 1:100
    Kommentare

    Expressed in intestinal mucosa, where it is detected in epithelial cells, endothelial cells, smooth muscle cells and immune cells, such as lymphocytes

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20C. Avoid freeze / thaw cycles.
  • Target
    MAPKBP1 (Mitogen-Activated Protein Kinase Binding Protein 1 (MAPKBP1))
    Andere Bezeichnung
    MAPKBP1 (MAPKBP1 Produkte)
    Synonyme
    MGC83682 antikoerper, JNKBP-1 antikoerper, 2810483F24Rik antikoerper, AW123212 antikoerper, Jnkbp1 antikoerper, mKIAA0596 antikoerper, mitogen-activated protein kinase binding protein 1 L homeolog antikoerper, mitogen-activated protein kinase binding protein 1 antikoerper, mitogen activated protein kinase binding protein 1 antikoerper, mapkbp1.L antikoerper, MAPKBP1 antikoerper, Mapkbp1 antikoerper
    Hintergrund
    This gene encodes a scaffold protein that regulates the JNK (c-Jun N-terminal kinase) and NOD2 (nucleotide-binding oligomerization domain-containing protein 2) signaling pathways. The encoded protein interacts with another related JNK pathway scaffold protein, WDR62, via a conserved dimerization domain, and enhances JNK signaling. This protein may play a role in bacterial immunity by binding to the NOD2 receptor and negatively regulating downstream antibacterial and pro-inflammatory signaling. Mutations in this gene that impair cellular localization of the encoded protein cause a form of nephronophthisis, an autosomal-recessive kidney disorder, in human patients.
    Molekulargewicht
    163.818 kDa
    Gen-ID
    23005
    UniProt
    O60336
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