KCNA5 Antikörper

Produktnummer ABIN265025

Produktdetails anti-KCNA5 Antikörper

Target: KCNA5 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 (KCNA5))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNA5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody reacts to Kv1.5 Potassium Channel.

Aufreinigung: Purified

Immunogen: Synthetic peptide derived from the rat Kv1.5 potassium channel conjugated to KLH.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: 5 - 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Details zu KCNA5

Target: KCNA5 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 (KCNA5))

Andere Bezeichnung: KCNA5 (KCNA5 Produkte)

Synonyme: KCNA5 antikoerper, kcna5 antikoerper, ATFB7 antikoerper, HCK1 antikoerper, HK2 antikoerper, HPCN1 antikoerper, KV1.5 antikoerper, PCN1 antikoerper, Kv1.5 antikoerper, Kv1 antikoerper, potassium voltage-gated channel subfamily A member 5 antikoerper, potassium channel, voltage gated shaker related subfamily A, member 5 antikoerper, potassium voltage-gated channel, shaker-related subfamily, member 5 antikoerper, KCNA5 antikoerper, kcna5 antikoerper, Kcna5 antikoerper

Hintergrund: The Kv1.5 potassium channel is a voltage-gated channel protein which belongs to the delayed rectifier class and to the Shaker potassium channel subfamily which includes Kv1.1, Kv1.2, Kv1.3 and Kv1.4. Potassium channels are mainly found in plasma membranes but are not generally distributed over the cell surface. Potassium channels catalyze the rapid permeation of potassium ions while rejecting biologically abundant potential competitors such as sodium, calcium and magnesium. Ion selectivity and high through put rate of potassium channels is accomplished by precise co-ordination of dehydrated potassium by the protein and multiple ion occupancy within the permeation pathway. All potassium channels carry out the formation of a transmembrane leak specific for potassium ions. Since cells almost universally maintain cytoplasmic potassium concentrations higher than those extracellularly, the opening of a potassium channel implies a negative ongoing change in electrical voltage across the cell membrane. This may result in termination of the action potential of electrically excitable cells including nerve, muscle and pancreatic beta cells. In non-excitable cells, potassium channels play important roles in the cellular potassium recycling required for electrolyte balance effected by the renal epithelium.Synonyms: HK2, HPCN1, KCNA5, KV1-5, Potassium voltage-gated channel subfamily A member 5, RCK7, RK4, Voltage-gated potassium channel subunit Kv1.5

Gen-ID: 3741

NCBI Accession: NP_002225

UniProt: P22460