DAB1 Antikörper (N-Term)

Produktnummer ABIN264969

Produktdetails anti-DAB1 Antikörper

Target: DAB1 (Disabled Homolog 1 (Drosophila) (DAB1))

Bindungsspezifität: N-Term

Reaktivität: Maus

Wirt: Schaf

Klonalität: Polyklonal

Konjugat: Dieser DAB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody recognizes Mouse DAB1 (Disabled 1) (N-term). Other species not tested.

Aufreinigung: Purified

Immunogen: Recombinant protein corresponding to amino acids 1 - 179 of mouse disabled coupled to a GST fusion protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: 1 - 5 μg/mL. Immunoprecipitation: 5 - 10 μg/mL. Positive Control: 293 cells transfected with Dab-1 HA tag.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, 0.08 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Details zu DAB1

Target: DAB1 (Disabled Homolog 1 (Drosophila) (DAB1))

Andere Bezeichnung: DAB1 (DAB1 Produkte)

Synonyme: AI956902 antikoerper, C630028C02Rik antikoerper, scm antikoerper, scr antikoerper, scrambler antikoerper, yot antikoerper, disabled-1 antikoerper, LOC100232823 antikoerper, si:dkey-242m13.1 antikoerper, DAB1 antikoerper, zgc:136547 antikoerper, DAB1, reelin adaptor protein antikoerper, disabled 1 antikoerper, disabled homolog 1 antikoerper, Dab, reelin signal transducer, homolog 1a (Drosophila) antikoerper, Dab, reelin signal transducer, homolog 1b (Drosophila) antikoerper, DAB1 antikoerper, Dab1 antikoerper, LOC100232823 antikoerper, dab1a antikoerper, dab1b antikoerper

Hintergrund: Disruption of the disabled-1 gene (Dab1) results in aberrant migration of neurons during development and disorganization of laminar structures throughout the brain. Dab1 is thought to function as an adaptor molecule in signal transduction processes. It contains a protein-protein interaction (PI) similar to the phosphotyrosine binding domain of the Shc oncoprotein, it is phosphorylated by the Src protein tyrosine kinase, and it binds to SH2 binding domains in a phosphotyrosine dependent manner. Disabled-1 acts downstream of reelin in a signalling pathway.Synonyms: Disabled homolog 1

Gen-ID: 13131

NCBI Accession: NP_034144

UniProt: P97318