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Antikörper
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anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Pol...
Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1) Antikörper
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| Klonalität |
Monoklonal (R4-5) |
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Wirt
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Reaktivität
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Applikation
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| Produktnummer |
ABIN264424 |
| Menge |
100 µg (Lot specific) |
| Preis |
410,00 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
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Produktmerkmale
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Synonyms: GNAI1, Guanine nucleotide-binding protein G(i) alpha-1 subunit
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Weitere Bezeichnung
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G protein alpha inhibitor 1
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Gen-ID
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2770
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Swiss-Prot
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P63096
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Immunogen
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Hybridoma produced by the fusion of spelocytes from BALB/c mice immunized withpartially purified rat brain Gai1 protein and mouse myeloma Ag8 (NS1) cells.
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Kreuzreaktivität
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Rind (Kuh), Meerschweinchen, Human, Maus, Ratte (Rattus)
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Isotyp
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IgG2b (Passende Sekundärantikörper)
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Klon
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R4-5
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Beschreibung
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GTP-binding proteins (G-proteins) play a critical role in signal transduction by couplingreceptors to effectors. The intracellular consequences of G-protein activation includesecond messenger generation (such as cyclic AMP, calcium and diacylglycerol), proteinphosphorylation, ion channel activation, gene induction, cell growth, and differentiation.
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Spezifität
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Recognizes a single band of 39-42kDa, identified as the G i1 protein. This antibody is highly specific to Gi alpha1 and shows no cross-reaction with transducin, Galphao, Gi alpha2, Gi alpha3, or Gis. ADP-ribosylation of alphai1 protein does not alter the reactivity of this antibody. Species: Human, Rat, Mouse, Cow and Guinea pig. Others not tested.
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Applikationshinweise
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Western Blot (1-5 µg/ml). Positive Control: IMR-5 cells or brain. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Konzentration
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Lot specific
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Reinigung
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Purified
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Buffer
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PBS containing 0.08% Sodium Azide as preservative.
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Lagerung
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Store the antibody at -20°C. Avoid repeated freezing and thawing. Shelf life: One year from despatch.
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1)", Typ "Antikörper" finden
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Wirte
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Maus (19), Kaninchen (8)
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Reaktivitäten
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Human (16), Ratte (Rattus) (14), Rind (Kuh) (8), Maus (7), Meerschweinchen (4), Huhn (1), Fruchtfliege (Drosophila melanogaster) (1), Schwein (1)
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Applikationen
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Western Blot (WB) (27), Immunhistochemie (Paraffinschnitte) (IHC (p)) (8), ELISA (3), Enzyme Immunoassay (EIA) (3), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (1), Immunpräzipitation (IP) (1)
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Alternativen 
