Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

Caspase 6 Antikörper

CASP6 Reaktivität: Human WB Wirt: Maus Monoclonal MCH2 14 1-190 unconjugated
Produktnummer ABIN264405
  • Target Alle Caspase 6 (CASP6) Antikörper anzeigen
    Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))
    Reaktivität
    • 137
    • 78
    • 36
    • 11
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 160
    • 9
    • 1
    Maus
    Klonalität
    • 149
    • 21
    Monoklonal
    Konjugat
    • 75
    • 16
    • 13
    • 9
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    Dieser Caspase 6 Antikörper ist unkonjugiert
    Applikation
    • 137
    • 68
    • 61
    • 41
    • 40
    • 30
    • 26
    • 17
    • 14
    • 13
    • 11
    • 5
    • 4
    • 3
    • 1
    Western Blotting (WB)
    Spezifität
    Detects proenzyme form of human Caspase-6 by Western blot.
    Produktmerkmale
    Synonyms: CASP-6, CASP6, MCH2, MCH-2, Apoptotic protease Mch-2
    Aufreinigung
    Purified
    Immunogen
    Hybridoma produced by the fusion of splenocytes from mice immunized with recombinanthuman capase-6 protein and mouse myeloma cells. Genename: CASP6
    Klon
    MCH2 14 1-190
    Isotyp
    IgG1
    Top Product
    Discover our top product CASP6 Primärantikörper
  • Applikationshinweise
    Western Blot. Positive Control: MCF-7 cell lysate.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.08 % Sodium Azide as preservative.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store the antibody at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: One year from despatch
    Haltbarkeit
    12 months
  • Target
    Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))
    Andere Bezeichnung
    Caspase-6 (CASP6 Produkte)
    Synonyme
    xCaspase-6 antikoerper, mch2 antikoerper, caspase-6 antikoerper, zgc:112960 antikoerper, CASP6 antikoerper, casp6 antikoerper, Mch2 antikoerper, mCASP-6 antikoerper, MCH2 antikoerper, caspase 6 L homeolog antikoerper, caspase 6 antikoerper, caspase 6, apoptosis-related cysteine peptidase antikoerper, group XIIA secretory phospholipase A2 antikoerper, caspase-6 antikoerper, casp6.L antikoerper, casp6 antikoerper, CASP6 antikoerper, CpipJ_CPIJ017008 antikoerper, Casp6 antikoerper
    Hintergrund
    Caspase-6 (Cysteine-Requiring Aspartate Proteases) is part of a family of intracellular cysteine proteases that cleave their substrates after aspartic acid residues. These proteases play an integral role in inducing apoptosis in cells. Procaspase-6 (Mch2), a member of the ICE/ced-3 subfamily, is an inactive proenzyme that is activated to form caspase-6 by proteolytic cleavage at certain aspartic acid residues. During cleavage, the N-terminal is removed and the proenzyme is converted into a large (p18) and small (p11) subunits. Caspase-6 has two isoforms produced by alternative splicing. Over-expression of the isoform of caspase-6 without its prodomain can induce apoptosis. The isoform does not seem to display proteolytic activity. Together with caspases-3 and -7, the isoform of caspase-6 is classified as an effector/execution caspase. Caspase-3, caspase-8 and caspase-10 can cleave procaspase-6. Active caspase-6 cleaves several other proteins such as lamins, NuMa and Keratin 18. A possible cleavage of caspases-8 and -10 in cytochrome-C dependent apoptosis was reported recently.Synonyms: Apoptotic protease Mch-2, CASP-6, CASP6, MCH-2, MCH2
    Gen-ID
    839
    UniProt
    P55212
    Pathways
    Apoptose, Caspase Kaskade in der Apoptose
Sie sind hier:
Kundenservice