PD-1 Antikörper (AA 21-167)
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- Target Alle PD-1 (PDCD1) Antikörper anzeigen
- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
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Bindungsspezifität
- AA 21-167
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser PD-1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody detects PDCD1.
- Produktmerkmale
- Synonyms: Protein PD-1, hPD-1, PDCD1, Programmed cell death protein 1
- Aufreinigung
- Protein-G affinity chromatography
- Immunogen
- Recombinant human PDCD1 (21-167aa) purified from E. coli
- Klon
- 4F12
- Isotyp
- IgG2b
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anti-Programmed Cell Death 1 (PDCD1) (AA 21-170) antibodyPDCD1 Reaktivität: Human FACS, WB, IHC, ELISA, ICC, Neut Wirt: Maus Monoclonal 3E12A10 unconjugated
anti-Programmed Cell Death 1 (PDCD1) (AA 21-170) antibodyPDCD1 Reaktivität: Human FACS, WB, IHC, ELISA, ICC, Neut Wirt: Maus Monoclonal 1D6F6 unconjugated
anti-Programmed Cell Death 1 (PDCD1) (AA 21-170) antibodyPDCD1 Reaktivität: Human WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
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anti-Programmed Cell Death 1 (PDCD1) (AA 1-288) antibodyPDCD1 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-Programmed Cell Death 1 (PDCD1) antibodyPDCD1 Reaktivität: Human, Non-Human Primate FACS, IHC (fro) Wirt: Maus Monoclonal EH12-2H7 unconjugated
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- Applikationshinweise
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ELISA. Western blot: 1: 500 (starting dilution) approx. 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1.0 mg/mL
- Buffer
- Phosphate-Buffered Saline ( pH 7.4) with 0.09 % Sodium Azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
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Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoidrepeated freezing and thawing.
Shelf life: one year from despatch. - Haltbarkeit
- 12 months
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- Target
- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
- Andere Bezeichnung
- CD279 / PD1 (PDCD1 Produkte)
- Hintergrund
- PDCD1 is an immunoreceptor that belongs to the immunoglobulin (Ig) superfamily, also known as Programmed Cell Death 1. It is expressed on activated T cell, B cells, myeloid cells and a subset of thymocytes. PDCD1 interacts with expressed PDL1 and PDL2 to inhibit the proliferation and activation of T cells and B cells. Both PDL1 and PDL2 are expressed in a wide variety of normal tissues including heart, lung, placenta, spleen and kidney. PDCD1 might be involved in the regulation of peripheral tolerance and may help prevent autoimmune diseases.Synonyms: PDCD1, Programmed cell death protein 1, Protein PD-1, hPD-1
- Gen-ID
- 5133
- UniProt
- Q15116
- Pathways
- Cancer Immune Checkpoints
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