Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) Antikörper (FITC)

Antigen: Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C)

Synonyme: BAFFR, CD268, BAFF-R, MGC138235, RGD1560810, TNFRSF13C

Klonalität: Monoklonal (11C1)

Wirt: Maus

Reaktivität: Human

Konjugat: FITC

Applikation: Durchflusszytometrie (FACS)

Produktnummer: ABIN262903

Produktbeschreibung

Weitere Bezeichnung: CD268 / BAFFR

Gen-ID: 115650

Immunogen: BAFF-R-L1.2 transfectants.

Isotyp: IgG1

Klon: 11C1

Beschreibung: B cell-activating factor receptor (BAFF-R) is a 19 kD type III membrane protein. Itbelongs to TNFR superfamily, also known as TNFRSF member 13C (TNFRSF13C),BAFF receptor 3 (BR3), or CD268. BAFF-R is expressed on mature B cells, B celllymphoma, and T cell subset. BAFF-R is the major receptor for BAFF/BLys (or TALL-1,THANK) which binds to TACI and BCMA as well. The interaction of BAFF with BAFF-Rpromotes NF- kappa B activation and plays predominant roles in B-cell maturation andsurvival as well as costimulates T cell activation and proliferation. TRAF3 is a BAFF-Rintracellularly associated protein, which negatively regulates BAFF-R-mediated NF-kappa B activation. Alternate Names: anti-TNFRSF13C antibody, anti-BAFF-R antibody, anti-BAFFR antibody, anti-BR3antibody, anti-BAFF Receptor antibody.

Spezifität: Species Reactivity: Human.

Anwendungen

Applikationshinweise: Positive Controls: Mature B cells, B cell lymphoma, T cell subset

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v)BSA (origin USA).

Lagerung: Store at 4C. Do not freeze.

Forschungsgebiet: Apoptose/Nekrose, Rezeptoren

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Human peripheral blood lymphocytes stained with 11C1 FITC