Hepatitis A Virus Cellular Receptor 2 (HAVCR2) Antikörper

Antigen: Hepatitis A Virus Cellular Receptor 2 (HAVCR2)

Synonyme: TIM3, KIM-3, TIMD3, Tim-3, FLJ14428, HAVCR2, MGC140131

Klonalität: Monoklonal (RMT3-23)

Wirt: Ratte

Reaktivität: Maus

Applikation: Durchflusszytometrie (FACS)

Produktnummer: ABIN262596

Produktbeschreibung

Weitere Bezeichnung: TIMD3 / HAVCR2

Isotyp: IgG2a  (Passende Sekundärantikörper)

Klon: RMT3-23

Beschreibung: Tim-3 is a transmembrane protein also known as T cell immunoglobulin and mucindomain containing protein-3. Tim-3 is expressed at high levels on Th1 lymphocytes andCD11b+ macrophages. Tim-3 has also been shown to exist as a soluble protein. Cellsexpressing Tim-3 are present at high levels in the CNS of animals at the onset ofexperimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytessecreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immuneresponses and promote immunological tolerance. Alternate Names: anti-HAVCR2 antibody, anti-Hepatitis A virus cellular receptor 2 antibody, anti-Kidneyinjury molecule 3 antibody, anti-KIM3 antibody, anti-T cell immunoglobulin and mucindomain containing 3 antibody, anti-T cell immunoglobulin mucin 3 antibody, anti-TIMD3antibody.

Spezifität: Species Reactivity: Mouse.

Anwendungen

Applikationshinweise: Positive Controls: Expressed on activated Th1 lymphocytes and CD11b+ macrophages

Buffer: Phosphate-buffered solution, pH 7.2. Preservative: 0.09% Sodium Azide.

Lagerung: Store at 4C. Do not freeze.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Mouse Tim-3 transfected cells stained with purified RMT3-23, followed by anti-rat IgG FITC