T Cell Receptor (TCR) Vb 8.3 Antikörper

Antigen: T Cell Receptor (TCR) Vb 8.3

Klonalität: Monoklonal (8C1)

Wirt: Maus

Reaktivität: Maus

Applikation: Durchflusszytometrie (FACS)

Produktnummer: ABIN262589

Produktbeschreibung

Isotyp: IgG2a  (Passende Sekundärantikörper)

Klon: 8C1

Beschreibung: The V beta8.3 TCR is a variant of the TCR beta chain. It is expressed by a subset ofperipheral blood T cells and is increased in response to some viral infections andtumors. T cells expressing the alpha/ beta T cell receptor use clonally distributed TCRsto recognize cell-bound antigens such as peptide/MHC complexes and viralsuperantigens. The alpha/ beta TCR is an oligomeric TCR complex composed ofcovalently bound alpha and beta chains involved in antigen recognition and thenon-covalently associated monomorphic proteins CD3 delta, gamma, epsilon, and ?chains. The 8C1 antibody has been used for the identification of T cells expressing Vbeta8.3 by flow cytometry. Alternate Names: anti-T Cell Receptor V beta 8.3 antibody.

Spezifität: Species Reactivity: Mouse.

Anwendungen

Applikationshinweise: Positive Controls: Expressed on a subset of peripheral T cells, increased frequency in some viral andtumor responses

Buffer: Phosphate-buffered solution, pH 7.2. Preservative: 0.09% Sodium Azide.

Lagerung: Store at 4C. Do not freeze.

Forschungsgebiet: Immunologie, Rezeptoren

Beschränkungen: Nur für Forschungszwecke einsetzbar