T Cell Receptor (TCR) Vb 7 Antikörper

Antigen: T Cell Receptor (TCR) Vb 7

Klonalität: Monoklonal (TR310)

Wirt: Ratte

Reaktivität: Maus

Applikation: Durchflusszytometrie (FACS), Immunpräzipitation (IP)

Produktnummer: ABIN262586

Produktbeschreibung

Immunogen: T cell lymphoma TK-1.

Isotyp: IgG2b  (Passende Sekundärantikörper)

Klon: TR310

Beschreibung: The TR310 antibody reacts with the mouse T cell receptor V beta7 segment . T cellsexpressing the alpha/ beta T cell receptor use clonally distributed TCRs to recognizecell-bound antigens such as peptide/MHC complexes and viral superantigens. The alpha/ beta TCR is an oligomeric TCR complex composed of covalently bound alphaand beta chains involved in antigen recognition and the non-covalently associatedmonomorphic proteins CD3 delta, gamma, epsilon, and zeta chains. The TR310antibody reacts with one such clonally distributed TCR beta chain known as V beta7. Vbeta7 is expressed on a small subpopulation of both CD4+ and CD8+ T cells. TheTR310 antibody has been used for the identification of V beta7 expressing T cells byflow cytometry and immunoprecipitation. Alternate Names: anti-T cell antigen receptor, beta polypeptide antibody, anti-T cell receptor V beta 7antibody, anti-T cell receptor, beta cluster antibody, anti-TCRB antibody, anti-TRBantibody.

Spezifität: Species Reactivity: Mouse.

Anwendungen

Applikationshinweise: Positive Controls: Expressed on a subpopulation of CD4+ and CD8+ T cells bearing the V #9467 T cellreceptor segment

Buffer: Phosphate-buffered solution, pH 7.2. Preservative: 0.09% Sodium Azide.

Lagerung: Store at 4C. Do not freeze.

Forschungsgebiet: Immunologie, Rezeptoren, Signaltransduktion

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Balb/c mouse splenocytes stained with CD3 (145-2C11) APC and purified TR310, followed by anti-rat IgG FITC