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Antikörper
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anti-Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) Antikörper
Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) Antikörper
| Antigen |
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| Synonyme |
HSD11B2, AME, AME1, HSD2, HSD11K, SDR9C3, MGC127544, MGC81883, 11-HSD2 |
| Klonalität |
Polyklonal |
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Wirt
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Reaktivität
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Applikation
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| Produktnummer |
ABIN262208 |
| Menge |
50 µg |
| Preis |
450,00 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
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Weitere Bezeichnung
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11-beta HSD2 / HSD11B2
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Gen-ID
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3291, 25117
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Swiss-Prot
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P80365
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Immunogen
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The immunogen for this antibody was a sequence from 181a.a. to 405a.a. fromHSD11B2(a 405a.a. long protein).
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Beschreibung
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HSD11B2 catalyzes the conversion of cortisol to the inactive metabolite cortisone. Theprotein modulates intracellular glucocorticoid levels, thus protecting the nonselectivemineralocorticoid receptor from occupation by glucocorticoids.Defects in HSD11B2 are the cause of apparent mineralocorticoid excess (AME). AME isa potentially fatal disease characterized by severe juvenile low-renin hypertension,sodium retention, hypokalemia and low levels of aldosterone. It often leads tonephrocalcinosis. Alternate Names: Anti-EC 1.1.1.- antibody, Anti-11-DH2 antibody, Anti-11-beta-hydroxysteroiddehydrogenase type 2 antibody, Anti-11-beta-HSD2 antibody, anti-AME antibody,anti-AME1 antibody, anti-HSD11K antibody, anti-HSD2 antibody, anti-hydroxysteroid 11beta dehydrogenase 2 antibody, anti-hydroxysteroid 11 beta dehydrogenase isoenzyme2 antibody.
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Spezifität
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Species Reactivity: This antibody is reactive against Human, chimpanzee, rat. Localization: Microsome. Theoretical Molecular Weight: 44127 Da.
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Applikationshinweise
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Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution:1:2000. Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signaldevelopment.
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Buffer
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Phosphate-Buffered Saline. Preservative: No Preservative.
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Lagerung
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Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2)", Typ "Antikörper" finden
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Wirte
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Kaninchen (7), Maus (2), Huhn (1)
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Reaktivitäten
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Human (10), Maus (4), Ratte (Rattus) (4), Rind (Kuh) (1), Affe (1), Schwein (1), Kaninchen (1)
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Applikationen
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Western Blot (WB) (9), ELISA (Detektionsantikörper) (4), Dot Blot (Dot) (1), Immunzytochemie (ICC) (1), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (1), Immunhistochemie (Paraffinschnitte) (IHC (p)) (1), Immunpräzipitation (IP) (1)
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Epitope
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AA 25-40 (1)
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Alternativen 
