Solute Carrier Organic Anion Transporter Family, Member 1B3 (SLCO1B3) Antikörper

Antigen: Solute Carrier Organic Anion Transporter Family, Member 1B3 (SLCO1B3)

Synonyme: LST3, OATP8, OATP1B3, SLC21A8, LST-3TM13, SLCO1B3, OATPC, Slco1b4, SLCO1B4, Slc21a10, oatp8, slc21a8, MGC108027

Klonalität: Monoklonal (MDQ)

Wirt: Maus

Reaktivität: Human

Applikation: Immunhistochemie (Gefrierschnitte) (IHC (fro)), Immunfluoreszenz (IF), Immunpräzipitation (IP), Western Blot (WB)

Produktnummer: ABIN261578

Produktbeschreibung

Weitere Bezeichnung: SLCO1B3 / OATP8

Gen-ID: 28234

Immunogen: Synthetic peptide corresponding ot residues M(a.a. 1) D Q N Q H L N K T A E A Q P SE N K K T R Y(a.a. 23) C of human OATP2.

Format: Supernatant

Isotyp: IgG1  (Passende Sekundärantikörper)

Klon: MDQ

Beschreibung: The OATPs (organic anion transporter polypeptides) are a family of transport proteinsthat have been found to mediate the uptake of organic ions into hepatocyte cells. Theseproteins fall into the solute carrier family 21A (SLC21A), and are expressed in liver,kidney, and brain. These polypeptides are involved in the excretion of potentially toxiccompounds and therefore play a role in the overall detoxification system of the body.Unlike other members of the OATP family, OATP2 and 8 have been detectedexclusively in the liver, and there is an 80% amino acid sequence homology betweenthese polypeptides. Other names for OATP2 include SLC21A6, OATP-C, and LST-1.

Spezifität: Species Reactivity: This antibody is reactive against Human.

Anwendungen

Applikationshinweise: Suggested working dilutions: immunofluorescence 1:20,Immunohistochemistry-Frozen 1:20

Buffer: Preservative: 0.01% sodium azide.

Lagerung: Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Publikationen

Publikationen: Cui, Koenig, Nies et al.: "Detection of the human organic anion transporters SLC21A6 (OATP2) and SLC21A8 (OATP8) in liver and hepatocellular carcinoma." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 83, Issue 4, pp. 527-38, 2003 (PubMed).