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Hematopoietic Cell-Specific Lyn Substrate 1 (HCLS1) Antikörper

Antigen

Hematopoietic Cell-Specific Lyn Substrate 1 (HCLS1)

Synonyme HS1, CTTNL, AW213261, HCLS1, MGC127454, hcls1
Klonalität Polyklonal
Wirt
Alternativen

Ziege

Reaktivität
Alternativen

Human

Applikation
Alternativen Western Blot (WB)
Produktnummer ABIN260666
Menge 0.1 mg  (0.5 mg/ml)
Preis 450,00 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 7 bis 10 Werktagen

Produktbeschreibung

Weitere Bezeichnung HCLS1
Gen-ID 3059, 15163
Immunogen Peptide sequence HFGLFPANYVKLLE corresponding to the C-terminus of HCLS1(NP_005326).
Isotyp IgG  (Passende Sekundärantikörper)
Beschreibung Hematopoietic cell specific Lyn substrate 1 (HCLS1) is an intracellular protein involvedin the signal transduction pathways in B and T lymphocytes. HCLS1 Tyr phosphorylationcatalyzed by Syk and Lyn plays a crucial role in the translocation of the protein to themembrane and is involved in the cytoskeleton rearrangement triggered by thrombin inhuman platelets. The gene is a substrate for caspase cleavage during apoptosis. Alternate Names: anti-Cortactin like antibody, anti-CTTNL antibody, anti-HCLS 1 protein antibody,anti-HCLS1 antibody, anti-HCLS1 protein antibody, anti-Hematopoietic cell specific Lynsubstrate 1 antibody, anti-Hematopoietic lineage cell specific protein antibody, anti-HS1antibody, anti-LckBP 1 antibody, anti-LckBP1 antibody, anti-p75 antibody.
Spezifität Recognizes human haematopoietic cell-specific lyn substrate 1 (HCLS1), a 75KDintracellular protein involved in the signal transduction pathways in lymphocytes.Expression of HCLS1 is restricted to cells of haematopoietic origin and is expressed inearly stages of myeloid and erythroid differentiation. Species Reactivity: Human. Based on sequence similarity, is expected to react with Mouse.

Anwendungen

Applikationshinweise Suggested working dilutions: Western Blot 2ug/ml - 4ug/ml
Konzentration 0.5 mg/ml
Buffer TRIS buffered saline pH7.3. Preservative: 0.02% Sodium Azide.
Lagerung Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Forschungsgebiet Signaltransduktion
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen

Alternativen zu Antigen "Hematopoietic Cell-Specific Lyn Substrate 1 (HCLS1)", Typ "Antikörper" finden
Wirte Maus (16), Kaninchen (14), Ziege (4)
Reaktivitäten Human (33), Maus (6), Ratte (Rattus) (3), Rind (Kuh) (2), Hund (2), Huhn (1)
Applikationen Western Blot (WB) (33), Immunhistochemie (Paraffinschnitte) (IHC (p)) (14), ELISA (11), Enzyme Immunoassay (EIA) (8), Immunhistochemie (IHC) (4), Immunfluoreszenz (IF) (3), ELISA (Detektionsantikörper) (2), Dot Blot (Dot) (1), Immunpräzipitation (IP) (1)
Epitope C-Term (2)