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Antikörper
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anti-Hematopoietic Cell-Specific Lyn Substrate 1 (HCLS1) Antikörper
Hematopoietic Cell-Specific Lyn Substrate 1 (HCLS1) Antikörper
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| Synonyme |
HS1, CTTNL, AW213261, HCLS1, MGC127454, hcls1 |
| Klonalität |
Polyklonal |
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Wirt
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Reaktivität
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Applikation
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| Produktnummer |
ABIN260666 |
| Menge |
0.1 mg (0.5 mg/ml) |
| Preis |
450,00 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
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Weitere Bezeichnung
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HCLS1
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Gen-ID
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3059, 15163
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Immunogen
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Peptide sequence HFGLFPANYVKLLE corresponding to the C-terminus of HCLS1(NP_005326).
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Isotyp
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IgG (Passende Sekundärantikörper)
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Beschreibung
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Hematopoietic cell specific Lyn substrate 1 (HCLS1) is an intracellular protein involvedin the signal transduction pathways in B and T lymphocytes. HCLS1 Tyr phosphorylationcatalyzed by Syk and Lyn plays a crucial role in the translocation of the protein to themembrane and is involved in the cytoskeleton rearrangement triggered by thrombin inhuman platelets. The gene is a substrate for caspase cleavage during apoptosis. Alternate Names: anti-Cortactin like antibody, anti-CTTNL antibody, anti-HCLS 1 protein antibody,anti-HCLS1 antibody, anti-HCLS1 protein antibody, anti-Hematopoietic cell specific Lynsubstrate 1 antibody, anti-Hematopoietic lineage cell specific protein antibody, anti-HS1antibody, anti-LckBP 1 antibody, anti-LckBP1 antibody, anti-p75 antibody.
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Spezifität
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Recognizes human haematopoietic cell-specific lyn substrate 1 (HCLS1), a 75KDintracellular protein involved in the signal transduction pathways in lymphocytes.Expression of HCLS1 is restricted to cells of haematopoietic origin and is expressed inearly stages of myeloid and erythroid differentiation. Species Reactivity: Human. Based on sequence similarity, is expected to react with Mouse.
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Applikationshinweise
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Suggested working dilutions: Western Blot 2ug/ml - 4ug/ml
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Konzentration
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0.5 mg/ml
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Buffer
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TRIS buffered saline pH7.3. Preservative: 0.02% Sodium Azide.
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Lagerung
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Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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Forschungsgebiet
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Signaltransduktion
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "Hematopoietic Cell-Specific Lyn Substrate 1 (HCLS1)", Typ "Antikörper" finden
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Wirte
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Maus (16), Kaninchen (14), Ziege (4)
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Reaktivitäten
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Human (33), Maus (6), Ratte (Rattus) (3), Rind (Kuh) (2), Hund (2), Huhn (1)
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Applikationen
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Western Blot (WB) (33), Immunhistochemie (Paraffinschnitte) (IHC (p)) (14), ELISA (11), Enzyme Immunoassay (EIA) (8), Immunhistochemie (IHC) (4), Immunfluoreszenz (IF) (3), ELISA (Detektionsantikörper) (2), Dot Blot (Dot) (1), Immunpräzipitation (IP) (1)
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Epitope
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C-Term (2)
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