K(lysine) Acetyltransferase 5 (KAT5) Antikörper

Antigen: K(lysine) Acetyltransferase 5 (KAT5)

Synonyme: PLIP, 60kDa, Tip55, Tip60, Htatip, Htatip1, AI839539, MGC117972, MGC95167, TIP, ESA1, TIP60, cPLA2, HTATIP, HTATIP1, 6121, CG6121, DmEG0007.7, Dmel/TIP60, DmelCG6121, DmelTIP60, dmHAG405, dTip60, dTIP60, EG0007.7, EG:EG0007.7

Klonalität: Monoklonal (3F9G7)

Wirt: Maus

Reaktivität: Human

Applikation: Enzyme Immunoassay (EIA), Immunhistochemie (Paraffinschnitte) (IHC (p)), Western Blot (WB)

Produktnummer: ABIN259942

Produktbeschreibung

Weitere Bezeichnung: KAT5

Gen-ID: 10524

Immunogen: Ni-NTA purified truncated recombinant TIP60-gst expressed in E. Coli strain BL21(DE3).

Isotyp: IgG2b  (Passende Sekundärantikörper)

Klon: 3F9G7

Beschreibung: HTATIP (HIV-1 Tat interacting protein TIP60, about 60kDa) belongs to the MYST familyof histone acetyl transferases (HATs) and was originally isolated as an HIV-1TAT-interactive protein. HATs play important roles in regulating chromatin remodeling,transcription and other nuclear processes by acetylating histone and nonhistoneproteins. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 andH4), is the primary building block of chromatin. In addition to the growing number ofpost-translational histone modifications regulating chromatin structure, cells can alsoexchange canonical histones with variant histones that can directly or indirectlymodulate chromatin structure. There are five major variants of histone H2A: canonicalH2A (most abundant), H2A.X, MacroH2A, H2ABbd and H2A.Z. Histone H2A.Z, the mostconserved variant across species, functions as both a positive and negative regulator oftranscription and is important for chromosome stability. Several homologous proteincomplexes, such as SWR-C, TIP60 and SRCAP (mammals), have been shown tocatalyze the ATP-dependent exchange of H2A.Z for H2A in the nucleosome. Thisprotein is a histone acetylase that has a role in DNA repair and apoptosis and is thoughtto play an important role in signal transduction. Alternate Names: anti-60 kDa Tat interactive protein antibody, anti-cPLA(2) interacting protein antibody,anti-HIV-1 Tat interactive protein antibody, anti-HTATIP antibody.

Spezifität: Species Reactivity: This antibody is reactive to Human.

Synonyme: PLIP, 60kDa, Tip55, Tip60, Htatip, Htatip1, AI839539, MGC117972, MGC95167, TIP, ESA1, TIP60, cPLA2, HTATIP, HTATIP1, 6121, CG6121, DmEG0007.7, Dmel/TIP60, DmelCG6121, DmelTIP60, dmHAG405, dTip60, dTIP60, EG0007.7, EG:EG0007.7

Anwendungen

Applikationshinweise: Suggested working dilutions: ELISA 1:10000,Western Blot 1:500- 1:2000 ,Immunohistochemistry-Paraffin 1:500-1:2000

Buffer: Ascitic fluid. Preservative: 0.03% sodium azide.

Lagerung: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

anti-K(lysine) Acetyltransferase 5 (KAT5) antibody

anti-K(lysine) Acetyltransferase 5 (KAT5) antibody (Image 2)