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CD14 Molecule (CD14) Antikörper (APC)
| Antigen | CD14 Molecule (CD14) |
| Synonyme | CD14 |
| Klonalität | Monoklonal (MEM-18) |
| Wirt |
Alternativen Maus |
| Reaktivität |
Alternativen Human, Affe |
| Konjugat |
Alternativen APC |
| Applikation |
Alternativen Durchflusszytometrie (FACS)
|
| Produktnummer | ABIN259688 |
| Menge | 100 Tests |
| Preis | 370,00 € Zzgl. Versandkosten €20,00 und MWSt |
| Lieferung nach |
|
| Verfügbarkeit | Lieferung in 7 bis 10 Werktagen |
Produktbeschreibung
| Weitere Bezeichnung | CD14 |
| Gen-ID | 929 |
| Swiss-Prot | 5q311 |
| Immunogen | A crude mixture of human urinary proteins precipitated by ammonium sulphate from theurine of a patient suffering from proteinuria. Reference Sequence: 5q31.1. |
| Isotyp | IgG1 |
| Klon | MEM-18 |
| Beschreibung | CD14 is a 55 kDa GPI-anchored glycoprotein, constitutively expressed on the surface ofmature monocytes, macrophages, and neutrophils, where serves as a multifunctionallipopolysaccharide receptor, it is also released to the serum both as a secreted andenzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in areaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serumprotein. The soluble sCD14 is able to discriminate slight structural differences betweenlipopolysaccharides and is important for neutralization of serum allochthonouslipopolysaccharides by reconstituted lipoprotein particles. CD14 affects allergic,inflammatory and infectious processes. |
| Spezifität | The antibody MEM-18 reacts with CD14, a 53-55 kDa GPI(glycosylphosphatidylinositol)-linked membrane glycoprotein expressed on monocytes,macrophages and weakly on granulocytes, also expressed by most tissuemacrophages. In human, the epitope recognized by MEM-18 is located between aminoacids 57-64.HLDA III, WS Code M 253HLDA IV, WS Code M 314HLDA V, WS Code M MA087HLDA VI, WS Code M MA95. Species Reactivity: Cross reacts with human and primate. Not tested on other species. |
Anwendungen
| Applikationshinweise | The reagent is designed for Flow Cytometry analysis of human blood cells using 10 mlreagent / 100 ml of whole blood or 10^6 cells in a suspension.The content of a vial (1 ml) is sufficient for 100 tests. |
| Buffer | The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodiumazide and 0.2% (w |
| Lagerung | Store in the dark at 2-8C. Do not freeze. Avoid prolonged exposure to light. Do not useafter expiration date stamped on vial label. Short-term exposure to room temperatureshould not affect the quality of the reagent.However, if reagent is stored under |
| Forschungsgebiet | Stammzellen, Angeborene Immunität, Hämopoetische Vorläufer, Hämatopoetische Stammzellen, CD Antigene, Oberflächenrezeptoren der Immunzellen , Apoptose/Nekrose, Immunologie, Inflammation |
| Beschränkungen | Nur für Forschungszwecke einsetzbar |
Alternativen
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