X-Box Binding Protein 1 (XBP1) Antikörper

Antigen: X-Box Binding Protein 1 (XBP1)

Synonyme: XBP2, TREB5, XBP-1, TREB-5, D11Ertd39e, cb918, treb5, trebf, xbp1a, xbp1b, id:ibd1195, wu:fb02h05, wu:fb63f10, HTF, xbp1, MGC53678, MGC130816, xbp2, xXBP1, MGC76163, XBP1, XBPP1, MGC127699

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Maus

Applikation: Immunfluoreszenz (IF), Western Blot (WB)

Produktnummer: ABIN258551

Produktbeschreibung

Weitere Bezeichnung: XBP1 / TREB5

Gen-ID: 7494

Immunogen: Synthetic peptide corresponding to 18 amino acids near the amino terminus of humanXBP-1(Genbank accession No. BAB82982).

Beschreibung: This gene encodes a transcription factor that regulates MHC class II genes by binding toa promoter element referred to as an X box. The protein contains two domainscommonly found in transcription factors that confer DNA binding and dimerizationcapability. This gene product was also separately identified as a cellular transcriptionfactor that binds to an enhancer in the promoter of the T cell leukemia virus type 1promoter. It may increase expression of viral proteins by acting as the DNA bindingpartner of a viral transactivator. There is also a recent finding that the same agents thatcause an ER stress response, the unfolded protein response, also increase transcriptionof this gene. This increase in transcription requires an ER stress response consensusbinding element in the promoter. Alternate Names: anti-Tax responsive element binding protein 5 antibody, anti-TREB5 antibody, anti-Xbox binding protein 1 antibody, anti-XBP2 antibody.

Spezifität: Reacts with human and mouse XBP-1. Recognizes the spliced and the non-splicedisoforms of XBP-1. Species Reactivity: Reacts in human and mouse. Not tested in other species.

Anwendungen

Applikationshinweise: Suggested working dilutions: Western Blot 1-2ug/ml,Immunocytochemistry . Positive Controls: L1210 cell lysate

Konzentration: 1.0 mg/ml

Buffer: PBS. Preservative: 0.02% Sodium azide.

Lagerung: Store at 4 degrees C long term.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

anti-X-Box Binding Protein 1 (XBP1) antibody