Stathmin / STMN1 pSer24 Antikörper

Antigen: Stathmin / STMN1 pSer24

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Maus, Ratte (Rattus)

Applikation: Immunhistochemie (Gefrierschnitte) (IHC (fro)), Western Blot (WB)

Produktnummer: ABIN257595

Produktbeschreibung

Gen-ID: 3925, 16765, 29332

Swiss-Prot: P16949

Immunogen: The antiserum was produced against synthesized phosphopeptide derived from humanStathmin 1 around the phosphorylation site of serine 24 (I-L-SP-P-R).

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: This protein is a ubiquitous cytosolic phosphoprotein proposed to function as anintracellular relay integrating regulatory signals of the cellular environment. The encodedprotein is involved in the regulation of the microtubule filament system by destabilizingmicrotubules. It prevents assembly and promotes disassembly of microtubules.Alternatively spliced transcript variants encoding the same protein have been identified. Alternate Names: anti-Lag antibody, anti-LAP 18 antibody, anti-LAP18 antibody, anti-Leukemia associatedphosphoprotein p18 antibody, anti-Metablastin antibody, anti-Oncoprotein 18 antibody,anti-OP 18 antibody, anti-OP18 antibody, anti-p18 antibody, anti-p19 antibody,anti-Phosphoprotein 19 antibody, anti-Phosphoprotein p19 antibody, anti-PP17antibody, anti-PP19 antibody, anti-PR22 antibody, anti-Pr22 protein antibody,anti-Prosolin antibody, anti-Protein Pr22 antibody, anti-SMN antibody, anti-Stathminantibody, anti-Stathmin1 antibody, anti-STMN 1 antibody, anti-STMN1 antibody.

Spezifität: Stathmin 1 (specific to Phospho-Ser24) antibody detects endogenous levels of Stathmin1 only when phosphorylated at serine 24.Phosphorylated:Ser24. Species Reactivity: This antibody is reactive against Human, Mouse, Rat.

Anwendungen

Applikationshinweise: Suggested working dilutions: Western Blot 1:500-1:1000,immunohistochemistry 1:50-1:100

Konzentration: 1.0 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, and 50%glycerol. Preservative: 0.02% Sodium Azide.

Lagerung: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Stathmin 1 (phospho-Ser24) antibody

Western blot analysis of extracts from Jurkat cells untreated or treated with PMA (1ng/ml, 15min), using Stathmin 1 (Ab-24) antibody ( Line 1 and 2) and Stathmin 1 (phospho-Ser24) antibody ( Line 3 and 4).