Serotonin (5-HT) Antikörper
| Antigen |
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| Klonalität |
Monoklonal (YC5-45) |
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Wirt
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Reaktivität
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Applikation
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 Alternativen Immunhistochemie (Gefrierschnitte) (IHC (fro)), Immunfluoreszenz (IF)
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| Produktnummer |
ABIN256002 |
| Menge |
0.1 ml |
| Preis |
480,00 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
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Immunogen
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Serotonin conjugated to Bovine Serum Albumin.
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Format
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Supernatant
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Isotyp
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IgG2 (Passende Sekundärantikörper)
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Klon
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YC5-45
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Beschreibung
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Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine neurotransmitter synthesizedin serotonergic neurons in the central nervous system and enterochromaffin cells in thegastrointestinal tract. Serotonin plays an important part in the biochemistry ofdepression, migraine, bipolar disorder and anxiety. It is also believed to be influential onsexuality and appetite. 5-HT is generally thought not to be released from synapticterminal buttons in the manner of classical neurotransmission but from serotonergicvaracosities into the extra neuronal space. From here it is free to diffuse over a relativelylarge region of space (>20um) and activate 5-HT receptors located on the dendrites,cell bodies and presynaptic terminals of adjacent neurons. Serotonergic action isterminated primarily via uptake of 5-HT from the synapse. This is through the specificmonoamine transporter for 5-HT, 5-HT reuptake transporter, on the presynaptic neuron.The pharmacology of 5-HT is extremely complex, with its actions being mediated by alarge and diverse range of 5-HT receptors. Useful for the diagnosis of carcinoid tumorsand the investigation of the effects of drugs on the neurological system. Alternate Names: anti-5 HT 5A antibody, anti-5 HT antibody, anti-5 HT5A antibody, anti-5hydroxytryptamine antibody, anti-5HT antibody.
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Spezifität
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Recognizes serotonin and does not cross react with 5-hydroxyindolacetic acid, GABA,noradrenaline, 5-hydroxytryptophan, carnosine or melatonin. Serotonin (also known as5-hydroxytryptamine or 5-HT) is a biochemical messenger and neurotransmittersynthesized from L-tryptophan. Serotonin has a range of functions, including regulationof gastric motility, and may be related to some psychiatric disorders includingschizophrenia and depression. Serotonin is widely distributed in the central andperipheral nervous system, and also in some non-neural tissues such as platelets.
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Buffer
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Preservative: 0.01%Thiomersal.
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Lagerung
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Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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Forschungsgebiet
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Hormone
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "Serotonin (5-HT)", Typ "Antikörper" finden
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Wirte
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Kaninchen (11), Ziege (2), Maus (2), Schaf (2), Ratte (1)
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Reaktivitäten
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Human (8), Säugetiere (6), Ratte (Rattus) (5), Maus (2), Alle Spezies (1), Meerschweinchen (1), Kaninchen (1), Xenopus laevis (1)
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Applikationen
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Immunhistochemie (Gefrierschnitte) (IHC (fro)) (12), Immunfluoreszenz (IF) (9), Immunhistochemie (Paraffinschnitte) (IHC (p)) (9), Enzyme Immunoassay (EIA) (2), Immunhistochemie (IHC) (1)
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