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NLRP6 Antikörper (AA 351-450)

NLRP6 Reaktivität: Maus, Ratte ELISA, IF (cc), IF (p), IHC (fro), ICC, IHC (p), IP Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2559652
  • Target Alle NLRP6 Antikörper anzeigen
    NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))
    Bindungsspezifität
    • 14
    • 10
    • 9
    • 8
    • 7
    • 6
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    AA 351-450
    Reaktivität
    • 32
    • 32
    • 17
    Maus, Ratte
    Wirt
    • 60
    • 1
    Kaninchen
    Klonalität
    • 61
    • 1
    Polyklonal
    Konjugat
    • 19
    • 6
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NLRP6 Antikörper ist unkonjugiert
    Applikation
    • 35
    • 35
    • 12
    • 12
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
    Kreuzreaktivität
    Maus, Ratte
    Homologie
    Human
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human NALP6
    Isotyp
    IgG
    Top Product
    Discover our top product NLRP6 Primärantikörper
  • Applikationshinweise
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    IP(1-2 μg)
    ICC 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))
    Andere Bezeichnung
    NALP6 (NLRP6 Produkte)
    Synonyme
    NLRP6 antikoerper, NALP6 antikoerper, AVR antikoerper, CLR11.4 antikoerper, NAVR antikoerper, NAVR/AVR antikoerper, PAN3 antikoerper, PYPAF5 antikoerper, AI504961 antikoerper, Avr antikoerper, Nalp6 antikoerper, Navr antikoerper, Navr/Avr antikoerper, Pypaf5 antikoerper, NLR family pyrin domain containing 6 antikoerper, NLR family, pyrin domain containing 6 antikoerper, NLRP6 antikoerper, Nlrp6 antikoerper
    Hintergrund

    Synonyms: AVR, NAVR, PAN3, NALP6, PYPAF5, CLR11.4, NAVR/AVR, NACHT, LRR and PYD domains-containing protein 6, Angiotensin II/vasopressin receptor, PYRIN-containing APAF1-like protein 5, NLRP6

    Background: May contribute to arginine-vasopressin (AVP)-mediated regulation of renal salt-water balance, glucose and lipid metabolism, apoptosis, and/or cell cycle. Binds arginine-vasopressin but not angiotensin II and acts as an arginine-vasopressin V2 receptor. Plays a role in modulating inflammatory responses in the colon to allow recovery from intestinal epithelial damage and limit tumorigenic potential. Protects against the development of colitis by controlling the composition of the gut microbiota by preventing colonization of the colon by harmful, inflammation-inducing bacteria such as Prevotella species. May mediate activation of CASP1 via ASC, promote activation of NF-kappa-B and stimulate cAMP accumulation (By similarity).

    Gen-ID
    171389
    UniProt
    P59044
    Pathways
    Inflammasome
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