T Cell Receptor (TCR) Vb 8.1, 8.2 Antikörper (PE)

Antigen: T Cell Receptor (TCR) Vb 8.1, 8.2

Klonalität: Monoklonal (KJ16)

Wirt: Ratte

Reaktivität: Maus

Konjugat: PE

Applikation: Durchflusszytometrie (FACS)

Produktnummer: ABIN255355

Produktbeschreibung

Isotyp: IgG1

Klon: KJ16

Beschreibung: T cell receptors (TCR) recognize foreign antigens which have been processed as smallpeptides and bound to major histocompatibility complex (MHC) molecules at the surfaceof antigen presenting cells (APC). Each T cell receptor is a dimer consisting of onealpha and one beta chain or one delta and one gamma chain. This region representsthe germline organization of the T cell receptor beta locus. The beta locus includes V(variable), J (joining), diversity (D), and C (constant) segments. During T celldevelopment, the beta chain is synthesized by a recombination event at the DNA leveljoining a D segment with a J segment, a V segment is then joined to the D-J gene. TheC segment is later joined by splicing at the RNA level. Alternate Names: Anti-T cell antigen receptor, beta polypeptide antibody, Anti-T cell receptor beta locusantibody, Anti-T cell receptor, beta cluster antibody, Anti-TCRB antibody, Anti-TRBantibody.

Spezifität: This antibody recognises the Vbeta8.1 and Vbeta8.2 determinants of the murine T cellreceptor. Species Reactivity: Mouse. Not yet tested in other species.

Anwendungen

Applikationshinweise: This antibody is useful for flow cytometry / FACS analysis. For FACS use 10ul of thesuggested working dilution to label 10^6 cells in 100ul.

Buffer: 0.5% BSA and Phosphate buffered saline pH7.4. Preservative: 0.09% Sodium Azide.

Lagerung: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Forschungsgebiet: Immunologie, Rezeptoren

Beschränkungen: Nur für Forschungszwecke einsetzbar